Antibiotics for Fever Among Children: Findings From the Surveillance for Enteric Fever in India Cohorts.

Background: Acute febrile illness in children is frequently treated with antibiotics. However, the inappropriate use of antibiotics has led to the emergence of multidrug-resistant pathogens.

Methods: We measured use of antibiotics for fever in 4 pediatric cohorts that were part of the Surveillance for Enteric Fever in India (SEFI) network.

Factors Predicting Blood Culture Positivity in Children With Enteric Fever.

Background: Blood culture, despite low sensitivity, is the gold standard for enteric fever diagnosis. Understanding predictors of blood culture positivity may help design strategies to optimize enteric fever diagnosis.

Methods: A cohort of 6760 children aged 0.

Why do participants drop-out: findings from a prospective pediatric cohort for fever surveillance established at Vellore, southern India.

Background: Cohort studies are pivotal in understanding the natural history, and to thereby determine the incidence of a disease. The conduct of large-scale community-based cohort studies is challenging with reference to money, manpower and time. Further, attrition inherent to cohort studies can affect the power, and thereby the study's validity.