Publications by authors named "Sathvik Panambur Aithala"

Purpose: To identify predictors of radiation-induced liver disease (RILD) in patients with hepatocellular carcinoma (HCC) treated with proton beam therapy (PBT).

Methods: This multicenter study included 136 patients with HCC (eastern, n = 102; western, n = 34) without evidence of intrahepatic tumor progression after PBT. The RILD was defined as ascites with alkaline-phosphatase abnormality, grade ≥3 hepatic toxicity, or Child-Pugh score worsening by ≥2 within 4 months after PBT completion.

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Article Synopsis
  • The study investigates the role of extranodal extension (ENE) and pathological nodal parameters in predicting outcomes for patients with node-positive salivary gland carcinoma who underwent surgery.
  • It analyzed data from 114 patients over a median follow-up of 69 months, finding that the number of metastatic nodes is a significant predictor for regional control, locoregional control, and overall survival, whereas ENE did not show a correlation with these outcomes.
  • The findings suggest that the number of metastatic nodes should be emphasized over ENE in staging criteria, indicating that incorporating ENE into existing guidelines may not enhance prognostic accuracy.
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