Publications by authors named "Satbir Jassal"
Background: Intranasal diamorphine is a potential treatment for breakthrough pain but few paediatric data are available to assist dose estimation.
Aim: To determine an intranasal diamorphine dose in children through an understanding of pharmacokinetics.
Design: A systematic review of the literature was undertaken to seek diamorphine pharmacokinetic parameters in neonates, children and adults.
Article Synopsis
- The DIPPER study aims to explore the feasibility of a future trial comparing oral and transmucosal opioids for managing breakthrough pain in pediatric palliative care, as no randomized trials or standardized measures currently exist.
- An expert panel used the nominal group technique to reach consensus on practices for administering transmucosal diamorphine, including dosing and pain measurement methods for children.
- The panel recommended the buccal route for administration and specific pain assessment tools suitable for different age groups, which will inform the design of a larger randomized controlled trial.
Context: Breakthrough pain (BTP) is common in cancer and other conditions yet there is a lack of validated BTP measurement tools.
Objectives: We aimed to identify all tools assessing or characterising BTP in patients of any age with any condition, and to critically appraise their psychometric properties.
Methods: The Cochrane Library, PROSPERO, Embase, CINAHL, Medline, PsycINFO, Web of Science, Google Scholar, ProQuest, Evidence Search and OpenGrey were searched to identify all available tools used to assess BTP.
Introduction: Breakthrough pain is common in children and adults with cancer and other conditions, including those approaching end-of-life, although it is often poorly managed, possibly partly due to a lack of validated assessment tools. This review aims to (1) identify all available instruments measuring breakthrough pain in infants, children, adolescents or adults and (2) critically appraise, compare and summarise the quality of the psychometric properties of the identified instruments using COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) criteria.
Methods And Analysis: Two searches will be carried out between October 2019 and January 2020, one for each aim of the review.
Background: Symptom management for infants, children and young people at end of life is complex and challenging due to the range of conditions and differing care needs of individuals of different ages. A greater understanding of these challenges could inform the development of effective interventions.
Aim: To investigate the barriers and facilitators experienced by patients, carers and healthcare professionals managing symptoms in infants, children and young people at end of life.
Introduction: This protocol describes the objective and methods of a systematic review of barriers and facilitators experienced by patients, carers and healthcare professionals when managing symptoms in infants, children and young people (ICYP) at end-of-life.
Methods And Analysis: The Cochrane Library, PROSPERO, CINAHL, MEDLINE, PsycINFO, Web of Science Core Collection, ProQuest Dissertations & Theses Database, Evidence Search and OpenGrey will be electronically searched. Reference screening of relevant articles and inquiries to researchers in the field will be undertaken.
The management of pain in pediatric palliative care (PPC) is essential. Whilst the field of pain management has developed over the years, much of what is done in PPC is based on anecdotal evidence or adult studies. This review explores recent developments in pain management in PPC, in particular the WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses.
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