Publications by authors named "Saskia L Herbert"
Article Synopsis
- This study evaluated the five-year overall, recurrence, and distant metastasis-free survival rates of high- and intermediate-risk breast cancer patients who chose not to undergo recommended adjuvant chemotherapy.
- Conducted as part of the BRENDA II multicenter cohort study from 2009 to 2012, findings were based on a total of 759 patients, analyzing the impact of chemotherapy decisions made by a multi-professional tumorboard team.
- Results showed that while there were no significant differences in overall survival and metastasis-free survival for patients who declined chemotherapy, those who followed the guidelines and received chemotherapy experienced a significantly better five-year recurrence-free survival.
Background/aim: There is a lack of data concerning the surgical treatment of locally advanced squamous cell carcinoma of the uterine cervix (LACC) with neoadjuvant and adjuvant chemotherapy (NACT, ACT) as well as total mesometrial resection (TMMR). The aim of the study was to present a novel approach for treating LACC using a tumor response score for NACT.
Patients And Methods: A total of 12 patients with LACC were treated with NACT [cisplatin, ifosfamide, paclitaxel (TIP)], TMMR and ACT containing TIP.