Publications by authors named "Saskia K Funk"
Article Synopsis
- In meiosis, the formation of DNA double-strand breaks (DSBs) by the protein Spo11 kickstarts recombination and is essential for proper chromosome segregation.
- Research focuses on Mer2, a key factor in the DSB machinery, showing it interacts with histone reader Spp1 and nucleosomes to help tether DSB factors to chromatin.
- The study identifies a crucial conserved region within Mer2 that interacts with the DSB factor Mre11, positioning Mer2 as a central player in coordinating essential protein complexes necessary for initiating meiotic recombination.
Background: Coral reefs are colored by eukaryotic chromoproteins (CPs) that are homologous to green fluorescent protein. CPs differ from fluorescent proteins (FPs) by intensely absorbing visible light to give strong colors in ambient light. This endows CPs with certain advantages over FPs, such as instrument-free detection uncomplicated by ultra-violet light damage or background fluorescence, efficient Förster resonance energy transfer (FRET) quenching, and photoacoustic imaging.
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