Publications by authors named "Saskia Dede Davi"

Article Synopsis
  • - **Prevalence of HIV**: Approximately 38.4 million people live with HIV globally, with a significant number (1.7 million) being children under 14, primarily in sub-Saharan Africa, where mother-to-child transmission is common and diagnoses are often delayed.
  • - **Case Report**: A 13-year-old boy from rural Gabon experienced repeated fever and fatigue for years, leading to multiple undiagnosed hospital visits. Ultimately, he was diagnosed with late-onset AIDS after serologic testing revealed HIV-1 infection.
  • - **Importance of Early Detection**: The case underlines the critical need for HIV testing in children and adolescents, especially in malaria-prone areas, as early diagnosis can significantly improve
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Background: Schistosome egg deposition in pregnant women may affect the placenta of infected mothers and cause placental schistosomiasis (PS). Histopathological examination of placental tissue is an inadequate detection method due to low sensitivity. So far, there has not been any systematic review on PS.

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Background: More than 20 million people are infected with L. loa, and around 40 million live in high or intermediate-risk areas in West- and Central Africa. Although loiasis is associated with significant morbidity and excess mortality, little is known about the perception of loiasis by affected communities.

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Snakebite envenoming (SBE) is a neglected tropical disease (NTD). Community-based studies from sub-Saharan Africa are urgently required as data on the incidence are scarce. This study aimed to determine the lifetime prevalence of snakebites in rural Gabon by preparing the conduct of a larger regional survey.

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Loa loa, the African eye worm, is a filarial pathogen transmitted by blood-sucking flies of the genus Chrysops. Loiasis primarily affects rural populations residing in the forest and adjacent savannah regions of central and west Africa, where more than 20 million patients are chronically infected in medium and high transmission regions. For a long time, loiasis has been regarded as a relatively benign condition.

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Infection with Schistosoma sp. during pregnancy can cause low birth weight of the newborn. To allow a better differentiation between newborns with low birth weight and those with normal weight, the terms of intrauterine growth restriction (IUGR), small for gestational age (SGA) or fetal growth restriction (FGR) should be used.

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Article Synopsis
  • A survey on HIV prevalence among pregnant women in Gabon revealed a 3.9% HIV positivity rate, providing much-needed epidemiological data for the country.
  • A co-infection study compared the prevalence of various infections between HIV-positive and HIV-negative pregnant women, finding that both groups had a significant rate of co-infections, but HIV-negative women tended to have more sexually transmitted infections.
  • The study suggests that HIV-positive women had a lower crude odds for sexually transmitted infections, hinting at different sexual risk factors that could influence infection rates in the population.
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Background: Loa loa and Mansonella perstans-the causative agents of loiasis and mansonellosis-are vector-borne filarial parasites co-endemic in sub-Saharan Africa. Diagnosis of both infections is usually established by microscopic analysis of blood samples. It was recently established that the odds for detecting Plasmodium spp.

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The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria.

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In this study, a rapid method for the detection of Central and West Africa clades of Monkeypox virus (MPXV) using recombinase polymerase amplification (RPA) assay targeting the G2R gene was developed. MPXV, an Orthopoxvirus, is a zoonotic dsDNA virus, which is listed as a biothreat agent. RPA was operated at a single constant temperature of 42°C and produced results within 3 to 10 minutes.

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