High-Risk Human Papillomavirus Detection via Cobas 4800 and REBA HPV-ID Assays.

Persistent infection with high-risk human papillomaviruses (HR-HPVs), particularly HPV16 and 18, has long been known to induce cervical cancer progression. However, given that a minority of HPV-infected women develop cancer, analysis of HR-HPV-infected women could help to predict who is at risk of acquiring cervical cancer. Therefore, to improve HR-HPVs detection, we used the FDA-approved cobas 4800 HPV and REBA HPV-ID HPV assays to detect HR-HPVs in colposcopy-derived cervical cells from 303 patients, detecting 72.