Publications by authors named "Sasikarn Pakdeeto"

Hemolytic disorders can cause severe morbidity or can be life-threatening. Before the recent development of practical and inexpensive testing for hemolysis by quantifying carbon monoxide in end-tidal breath, some hemolytic disorders in perinatal patients were not detected until severely problematic hyperbilirubinemia and/or anemia occurred. Here we review studies aimed at establishing the normal reference intervals for end tidal breath carbon monoxide (ETCO) in various perinatal populations.

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Background: Intra-amniotic infection has a strong causal association with spontaneous preterm birth and preterm prelabor rupture of membranes (PPROM). The most common route of intra-amniotic infection is the ascending pathway in which microorganisms from the vagina gain access to the amniotic cavity. Distant microorganisms such as those from the oral cavity have been reported in intra-amniotic infection through hematogenous spreading.

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Epidermolysis bullosa (EB) is a rare and genetically heterogeneous disorder characterized by skin fragility and blister formation occurring spontaneously or after minor trauma. EB is accompanied by congenital absence of skin (EB with CAS) in some patients. Pathogenic variants of are responsible for EB with CAS in the vast majority of cases.

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Objectives: We constructed reference intervals for end-tidal carbon monoxide (ETCOc) levels of neonates 28 to 34 weeks gestation in order to assess hemolytic rate.

Study Design: This is a prospective four-NICU study in Bangkok, Thailand, and Utah, USA.

Results: Of 226 attempted measurements, 92% were successful.

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