Publications by authors named "Sasidharan Salini"

This study explores innovative drywell designs for managed aquifer recharge (MAR) in agricultural settings, focusing on smaller diameter and deeper drywells, including the repurposing of dried or abandoned wells. Numerical simulations assessed the impact of drywell diameter (5-120 cm), depth (15-55 m), screen height, and subsurface heterogeneity on infiltration (I) and recharge (R) volumes over a one-year period under constant head conditions. Results indicate that smaller diameter drywells can effectively infiltrate and recharge significant water volumes.

View Article and Find Full Text PDF

Field measurements of hydrologic tracers indicate varying magnitudes of geochemical separation between subsurface pore waters. The potential for conventional soil physics alone to explain isotopic differences between preferential flow and tightly-bound water remains unclear. Here, we explore physical drivers of isotopic separations using 650 different model configurations of soil, climate, and mobile/immobile soil-water domain characteristics, without confounding fractionation or plant uptake effects.

View Article and Find Full Text PDF
Article Synopsis
  • Drywells (DWs) and infiltration basins (IBs) are used for managing stormwater and recharging groundwater, but no prior research has directly compared their performance under the same conditions.
  • A numerical study utilizing HYDRUS software revealed that a larger IB area increases infiltration and accelerates recharge, although DWs ultimately excel in recharge volume after extended simulation periods.
  • Findings suggest that DWs can outperform IBs in terms of efficiency and practicality, particularly in dealing with low permeable layers, making them a potentially superior choice for groundwater recharge with advantages like lower maintenance and contamination concerns.
View Article and Find Full Text PDF
Article Synopsis
  • Many arid regions struggle with water quality and availability for growing populations, highlighting the importance of drywells for stormwater capture and aquifer recharge.
  • This study used numerical experiments to investigate how viruses behave and move away from drywells in different soil conditions, finding that virus concentration can remain high even up to 22 meters away.
  • Results showed that virus removal efficiency is influenced by soil heterogeneity, with certain configurations enhancing virus movement and suggesting that traditional distance guidelines for protecting water quality may need to be reassessed.
View Article and Find Full Text PDF

Colloid aggregation and retention in the presence of macromolecular coatings (e.g., adsorbed polymers, surfactants, proteins, biological exudates, and humic materials) have previously been correlated with electric double layer interactions or repulsive steric interactions, but the underlying causes are not fully resolved.

View Article and Find Full Text PDF

Drywells are widely used as managed aquifer recharge devices to capture stormwater runoff and recharge groundwater, but little research has examined the role of subsurface heterogeneity in hydraulic properties on drywell recharge efficiency. Numerical experiments were therefore conducted on a 2D-axisymmetric domain using the HYDRUS (2D/3D) software to systematically study the influence of various homogenous soil types and subsurface heterogeneity on recharge from drywells under constant head conditions. The mean cumulative infiltration () and recharge () volumes increased with an increase in the saturated hydraulic conductivity ( ) for various homogeneous soils.

View Article and Find Full Text PDF
Article Synopsis
  • Drywells are being utilized more frequently for stormwater management and aquifer recharge, yet the effects of subsurface soil variability on their efficiency have not been extensively studied.
  • Numerical experiments using HYDRUS software revealed that having high permeability layers at the bottom of drywells significantly boosts infiltration rates, especially with larger horizontal extents of these layers.
  • It was also found that accurately determining soil properties from drywell performance is feasible for simple soil structures, but challenging for complex, realistic soil heterogeneities, suggesting the replacement of heterogeneous profiles with equivalent homogeneous ones for analysis.
View Article and Find Full Text PDF

The nature of the protein corona forming on biomaterial surfaces can affect the performance of implanted devices. This study investigated the role of surface chemistry and wettability on human serum-derived protein corona formation on biomaterial surfaces and the subsequent effects on the cellular innate immune response. Plasma polymerization, a substrate-independent technique, was employed to create nanothin coatings with four specific chemical functionalities and a spectrum of surface charges and wettability.

View Article and Find Full Text PDF

The influence of virus type (PRD1 and ΦX174), temperature (flow at 4 and 20°C), a no-flow storage duration (0, 36, 46, and 70 d), and temperature cycling (flow at 20°C and storage at 4°C) on virus transport and fate were investigated in saturated sand-packed columns. The vast majority (84-99.5%) of viruses were irreversibly retained on the sand, even in the presence of deionized water and beef extract at pH = 11.

View Article and Find Full Text PDF

Drywells are increasingly used for stormwater management and enhanced aquifer recharge, but only limited research has quantitatively determined the performance of drywells. Numerical and field scale experiments were, therefore, conducted to improve our understanding and ability to characterize the drywell behavior. In particular, HYDRUS (2D/3D) was modified to simulate transient head boundary conditions for the complex geometry of the Maxwell Type IV drywell; i.

View Article and Find Full Text PDF

Parasporins, a class of non-insecticidal crystal proteins of Bacillus thuringiensis (Bt) are being explored as promising anticancer agents due to their specific toxicity to cancer cells. The present study has identified 25 Bt isolates harbouring parasporin genes from Western Ghats region, the hotspot of biodiversity in India. Among these, the isolate, KAU 41 (Kerala Agricultural University isolate 41) contained non-hemolytic homogenous crystals showing specific cytotoxicity towards cancer cells.

View Article and Find Full Text PDF

(Fabaceae) is a prime ingredient in , a well-known Ayurvedic preparation for gynecological ailments. Due to scarcity, adulteration or substitution of related raw drugs is a common practice in its preparation. The bark of (Roxb.

View Article and Find Full Text PDF

All natural surfaces exhibit nanoscale roughness (NR) and chemical heterogeneity (CH) to some extent. Expressions were developed to determine the mean interaction energy between a colloid and a solid-water interface, as well as for colloid-colloid interactions, when both surfaces contain binary NR and CH. The influence of heterogeneity type, roughness parameters, solution ionic strength (IS), mean zeta potential, and colloid size on predicted interaction energy profiles was then investigated.

View Article and Find Full Text PDF

Escherichia coli transport and release experiments were conducted to investigate the pore-water velocity (v) dependency of the sticking efficiency (α), the fraction of the solid surface area that contributed to retention (S), the percentage of injected cells that were irreversibly retained (M), and cell release under different (10-300mM) ionic strength (IS) conditions. Values of α, S, and M increased with increasing IS and decreasing v, but the dependency on v was greatest at intermediate IS (30 and 50mM). Following the retention phase, successive increases in v up to 100 or 150mday and flow interruption of 24h produced negligible amounts of cell release.

View Article and Find Full Text PDF

The influence of temperature on virus (PRD1 and ΦX174) and carboxyl-modified latex nanoparticle (50 and 100nm) attachment was examined in sand-packed columns under various physiochemical conditions. When the solution ionic strength (IS) equaled 10 and 30mM, the attachment rate coefficient (k) increased up to 109% (p<0.0002) and the percentage of the sand surface area that contributed to attachment (S) increased up to 160% (p<0.

View Article and Find Full Text PDF

Context Considering the role of cellular oxidative stress in mutations and subsequent transformation, phytochemicals with antioxidant potential has become a primary choice as chemopreventives. Apodytes dimidiata E. Mey.

View Article and Find Full Text PDF

The transport and retention of Escherichia coli and bacteriophages (PRD1, MS2 and ФX174), as surrogates for human pathogenic bacteria and viruses, respectively, were studied in the sand that was amended with several types of biochar produced from various feedstocks. Batch and column studies were conducted to distinguish between the role of attachment and straining in microbe retention during transport. Batch experiments conducted at various solution chemistries showed negligible attachment of viruses and bacteria to biochar before or after chemical activation.

View Article and Find Full Text PDF

Background: Scutellaria baicalensis is a well-known plant in traditional Chinese medicine. Recently, several Scutellaria species with therapeutic potential have been recognized worldwide. Scutellaria colebrookiana and Scutellaria violacea, native to the Western Ghats of India, are reported to possess free radical scavenging efficacy.

View Article and Find Full Text PDF
Article Synopsis
  • Apodytes dimidiata, part of the Icacinaceae family, is known in Zulu traditional medicine for treating inflammation and gastrointestinal issues.
  • The methanolic extract from A. dimidiata leaves showed significant cytotoxic effects against various cancer cell lines, with the most potent active fraction having IC50 values between 0.92 to 3.95 µg/mL.
  • Administration of this active fraction in mice significantly reduced tumor volume by 55.14% and increased lifespan by 44.65%, with the iridoid glycoside genipin identified as the key active component through advanced purification techniques.
View Article and Find Full Text PDF

Background: Estrogen-mediated uterus endometrium instability is considered as one of the etiological factors in dysfunctional uterine bleeding (DUB) and uterine cancer. Saraca asoca (Family: Fabaceae) and its fermented preparation, Asokarishta, are extensively used as uterine tonic to treat gynecological disorders in Ayurveda. The present study evaluated the effect of S.

View Article and Find Full Text PDF