Publications by authors named "Sasha G Demeulenaere"
Article Synopsis
- Parthenolide, derived from the feverfew plant, shows anti-inflammatory and anti-cancer properties, and this study aims to understand its mechanism in breast cancer cells.
- Using advanced chemoproteomic techniques, researchers discovered that parthenolide covalently modifies a specific cysteine in focal adhesion kinase 1 (FAK1), disrupting its signaling pathways.
- This impairment results in reduced breast cancer cell growth, survival, and movement, highlighting an important target for other natural anti-cancer compounds.
