Synopsis of recent research by authors named "Saseela Atwal"
- Saseela Atwal's research primarily focuses on the aryl hydrocarbon receptor (AHR) and its activation, which is critical for understanding toxicological effects resulting from various environmental and pharmaceutical exposures.
- The study titled "Development and Application of a Dual Rat and Human AHR Activation Assay" presents a novel methodology that enhances the assessment of AHR activation through a dual-species approach, addressing limitations of older methods that were either cost-prohibitive or lacked resolution.
- Findings indicate that prolonged AHR activation can lead to significant toxicities, highlighting the importance of improved testing assays for evaluating the safety of new pharmaceutical compounds and their potential risks in preclinical models and humans.
