An implantable microactuated intrafascicular electrode for peripheral nerves.

Important advancements have been recently achieved in the field of neural interfaces to restore lost sensory and motor functions. The aim of this letter was to develop an innovative approach to increase the selectivity and the lifetime of polyimide-based intrafascicular electrodes. The main idea was to obtain a neural interface that is able to restore a good signal quality by improving the electrical connection between the active sites and the surrounding axons.

An optically powered single-channel stimulation implant as test system for chronic biocompatibility and biostability of miniaturized retinal vision prostheses.

A microsystem based microimplant with an optically powered single-channel stimulator was designed and developed as test system for an epi-retinal vision implant. Biostability of the hybrid assembly and the encapsulation materials were evaluated in pilot experiments in chronic implantations in a cat animal model. The implant was fabricated on a flexible polyimide substrate with integrated platinum electrode, interconnection lines, and contact pads for hybrid integration of electronic components.