Publications by authors named "Sasalaksamon Chanachai"

Background: The ongoing COVID-19 pandemic and the current shortage of speech-language pathologists in Thailand have limited access to speech services for children with cleft palate with or without cleft lip (CP± L). A combination of telepractice (TP) and face-to-face therapy could address the lack of continuous service and improve accessibility to speech therapy providers. This study aimed to compare the percentage of consonants correct (PCC) before and after speech therapy in children with CP± L.

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Background: Depression is significant mental health issue among university students and can decrease their ability to succeed academically. While various factors associated with mental health problems have been identified, researchers are increasingly exploring the role of positive mental health, such as character strengths and inner strengths, in relation to mental health problems.

Objective: This study aims to build upon previous research by examining the influence of positive mental health on the mediation model of depression among students enrolled at Chiang Mai University.

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A workforce with the adequate field epidemiology knowledge, skills and abilities is the foundation of a strong and effective animal health system. Field epidemiology training is conducted in several countries to meet the increased global demand for such a workforce. However, core competencies for field veterinary epidemiology have not been identified and agreed upon globally, leading to the development of different training curricula.

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Background And Aim: Marek's disease (MD) is a common lymphoproliferative disease affecting chickens and causing economic losses in commercial poultry. The MD outbreak was noticed in the southern part of Thailand in 2019. The suspected cases were found with an abnormal number of cases of layers dying with clinical signs, for example, weakness and emaciation, with evidence of MD gross lesions.

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Mastitis in dairy cattle can lead to significant financial losses due to a reduction in milk yield, the withdrawal period after treatment when milk cannot be sold, and an increase in somatic cell count (SCC) which can reduce the milk's per liter commercial value. Dairy cooperatives point at high-SCC problems as an important factor leading to suboptimal levels of milk quantity and quality. This study aims at describing farm characteristics and milking practices associated with high SCC, identifying risk factors, and assessing the economic loss due to high SCC in three dairy cooperatives in Chiang Mai, Thailand.

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White spot lesions around orthodontic brackets are the major complication during fixed orthodontic treatment. This study prepared orthodontic adhesives for promoting mineral precipitation and reducing bacterial growth. Adhesives with added calcium phosphate monohydrate/Sr-bioactive glass nanoparticles (Sr/CaP) and andrographolide were prepared.

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Enamel demineralization around orthodontic adhesive is a common esthetic concern during orthodontic treatment. The aim of this study was to prepare orthodontic adhesives containing monocalcium phosphate monohydrate (MCPM) and nisin to enable mineralizing and antibacterial actions. The physicomechanical properties and the inhibition of growth of the adhesives with added MCPM (5, 10 wt %) and nisin (5, 10 wt %) were examined.

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(1) Background: Thailand has made significant progress in reducing the number of human and animal rabies cases. However, control and elimination of the last remaining pockets of dog-mediated rabies have shown to be burdensome, predominantly as a result of the large numbers of free-roaming dogs without an owner that cannot be restrained without special efforts and therefore remain unvaccinated. To reach these dogs, the feasibility, and benefits of oral rabies vaccination (ORV) as a complementary tool has been examined under field conditions.

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Article Synopsis
  • Applied research focusing on oral vaccination of dogs is vital for tackling dog-mediated rabies, but it remains underutilized due to insufficient data on vaccine performance.* -
  • A study assessed the long-term immune response in Thai dogs given the oral rabies vaccine strain SPBN GASGAS, comparing various administration methods and control groups over a year.* -
  • Both oral and injectable vaccines triggered similar immune responses, with the oral vaccine showing sustained antibody presence; IgM appeared first, followed by a dominant IgG2 response regardless of the vaccine type.*
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To evaluate the localization of functional deficit area in epileptogenic zones of the brain in seven refractory and seven non-refractory epilepsy dogs using technetium 99m labeled with ethyl cysteinate dimer and interictal single photon emission computed tomography [Tc-ECD SPECT] co-registration with Magnetic Resonance Imaging (MRI). Regions showing perfusion deficits in the SPECT images were analyzed by using the standard semiquantitative evaluation method to compare the level of cortical perfusion to the maximum number of counts within the cerebellum (max C), considered the area of reference. This study showed that SPECT imaging revealed abnormalities in several regions of the brain in both epilepsy groups.

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Objective: The current study was conducted to improve the understanding of relationships between regional cortical amyloid load, glucose metabolism, cortical morphology (volume), and severity of clinical symptoms in patients with AD, MCI, and age-matched controls.

Methods: To objectivize the radiological evaluation of patients with suspected AD, head-to-head multi-modality imaging studies were conducted using MRI and PET/CT with [F]FDG and [F]AV45 for visualization and quantitation of brain morphology, glucose metabolism, and amyloid levels, respectively. A total of 84 subjects was studied, including 33 patients with AD, 31 patients with MCI, and 20 age-matched healthy controls (HC).

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Rabies is a major neglected zoonotic disease and causes a substantial burden in the Asian region. Currently, Pacific Oceania is free of rabies but enzootic areas throughout southeast Asia represent a major risk of disease introduction to this region. On September 25-26, 2019, researchers, government officials and related stakeholders met at an IABS conference in Bangkok, Thailand to engage on the topic of human rabies mediated by dogs.

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African swine fever (ASF) is a highly contagious disease that infects porcine species and has a major impact on the pig industry. Thailand imported approximately4 million kilograms of pig products from Italy in 2015 during the same time as an ASF outbreak was occurring on the island of Sardinia in Italy, thereby posing a potential risk of introduction of ASF virus (ASFV) into Thailand. To estimate whether or not importing pig products from Italy is a risk for Thailand and to identify gaps in control and prevention measures, risk analysis was performed.

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Objectives: This study aimed to identify occupational risk factors for brucellosis among small scale goat farmers in Thailand.

Methods: To better understand farmers' knowledge, attitudes and practices associated with brucellosis we interviewed 51 farmers and tested 314 goats for Brucella melitensis.

Results: All serological samples tested negative for Brucella infection.

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(1) Background: As part of the ongoing endeavor to eliminate dog-mediated human rabies in Thailand, renewed interest has been shown in oral vaccination of dogs as a supplementary tool to increase vaccination coverage of the dog population. (2) Methods: Three different bait types were tested using a hand-out model on the campus of the Kasetsart University and the surrounding temples in Thailand during September 2017, consisting of two industrial manufactured baits (fish meal and egg-flavored) and one bait made from local material (boiled pig intestine placed in collagen casing). A PVC-capsule containing dyed water was inserted in the bait.

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Background: Aiming for early disease detection and prompt outbreak control, digital technology with a participatory One Health approach was used to create a novel disease surveillance system called Participatory One Health Disease Detection (PODD). PODD is a community-owned surveillance system that collects data from volunteer reporters; identifies disease outbreak automatically; and notifies the local governments (LGs), surrounding villages, and relevant authorities. This system provides a direct and immediate benefit to the communities by empowering them to protect themselves.

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In Thailand, brucellosis re-emerged in humans in 2003 and is considered a public health risk to goat farmers as the disease is endemic in small ruminants. The Thai Department of Livestock Development (DLD) established a nationwide surveillance system for brucellosis in goats and sheep in 1997. Using data from this surveillance system, we describe the seroprevalence of brucellosis from 2013 to 2015 in small ruminants and the spatial distribution of the disease throughout Thailand.

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Background: Circulating thyrotropin receptor messenger ribonucleic acid (TSHR mRNA) assay has been validated in the follow-up of differentiated thyroid carcinoma (DTC) because of its high sensitivity during thyroid hormone therapy and no interference with endogenous anti-thyroglobulin antibodies (TgAb) compared to serum thyroglobulin (Tg). We investigated the efficacy of TSHR mRNA assay in 160 DTC patients using quantitative PCR (qPCR).

Findings: Only TSHR mRNA level of structural persistent disease with TgAb-positive (3.

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This study was conducted to determine the prevalence of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in pigs, farm workers, and the environment in northern Thailand, and to assess LA-MRSA isolate phenotypic characteristics. One hundred and four pig farms were randomly selected from the 21,152 in Chiang Mai and Lamphun provinces in 2012. Nasal and skin swab samples were collected from pigs and farm workers.

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Background: Porcine reproductive and respiratory syndrome (PRRS) has become a worldwide endemic disease of pigs. In 2006, an atypical and more virulent PRRS (HP-PRRS) emerged in China and spread to many countries, including Thailand. This study aimed to provide a first description of the spatio-temporal pattern of PRRS in Thailand and to quantify the statistical relationship between the presence of PRRS at the sub-district level and a set of risk factors.

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For infectious diseases such as highly pathogenic avian influenza caused by the H5N1 virus (A/H5N1 HP), early warning system is essential. Evaluating the sensitivity of surveillance is a necessary step in ensuring an efficient and sustainable system. Stochastic scenario tree modeling was used here to assess the sensitivity of the A/H5N1 HP surveillance system in backyard and free-grazing duck farms in Thailand.

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This study was conducted to investigate space and time clusters of highly pathogenic avian influenza A (H5N1) virus infection and to determine risk factors at the subdistrict level in Thailand. Highly pathogenic avian influenza A (H5N1) was diagnosed in 1890 poultry flocks located in 953 subdistricts during 2004-2007. The ecologic risk for H5N1 virus infection was assessed on the basis of a spatial-based case-control study involving 824 case subdistricts and 3296 control subdistricts from 6 study periods.

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On August 5, 2005, a private hospital reported a large number of students with gastrointestinal illness from the same school in Bangkok, Thailand. The Bureau of Epidemiology along with the Bangkok Metropolitan Administration investigated this outbreak, to determine risk factors, identify the source of infection and possible causative organism, and recommend prevention and control strategies. A case was defined as a person who was studying or working at School A and who developed abdominal pain, diarrhea, nausea or vomiting during the five-day period of August 4 to 8, 2005.

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Article Synopsis
  • - A new species of Leishmania is identified as the cause of a rare case of visceral leishmaniasis in a Thai man from Southern Thailand.
  • - Genetic testing showed differences between this new species and known Leishmania species, indicating it could be a distinct pathogen.
  • - The presence of antibodies in domestic cats suggests a broader exposure, highlighting the need for a large-scale epidemiological study on leishmaniasis, which is becoming a significant public health issue in Thailand.
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