Publications by authors named "Sarvgna K Raval"
Article Synopsis
- Exercise is a key treatment for post-traumatic osteoarthritis (PTOA) and may help clear inflammatory substances from the joints, potentially providing therapeutic benefits.
- This study involved inducing PTOA in rats through surgery, followed by a mild treadmill exercise regimen, which helped assess its effects on joint health and function.
- Results showed that exercise reduced joint damage, improved gait, and increased the rate of joint clearance, indicating it could be an effective approach to managing PTOA progression.
Significance: Changes in interstitial fluid clearance are implicated in many diseases. Using near-infrared (NIR) imaging with properly sized tracers could enhance our understanding of how venous and lymphatic drainage are involved in disease progression or enhance drug delivery strategies.
Aim: We investigated multichromatic NIR imaging with multiple tracers to assess in vivo microvascular clearance kinetics and pathways in different tissue spaces.