Problem: Considering the potential adverse effects of anticoagulation in abortion treatment, we investigate whether antioxidants might exert the same immunoprotection. Although the fertility properties of Vitamin E have been associated with its antioxidant capacity, its effect on cytokine balance during pregnancy is still unknown.
Method Of Study: Pregnant females from CBA/J × DBA/2 abortion model were orally supplemented with Vitamin E or inoculated intraperitoneally with enoxaparin.
Problem: CBA/J x DBA/2 abortion rate could be the consequence of a deficient local production of T helper (Th2) cytokines, which cause fetal wastage via fgl2 prothrombinase. Heparin reduces significantly the abortion rate in mice and recurrent spontaneous abortion (RSA) patients. We proposed to determine the effect of enoxaparin on the levels of local interleukin (IL)-6 during murine pregnancy.
View Article and Find Full Text PDFWe present a spatio-temporal operator formalism and beam propagation simulations that describe the broadband efficient adaptive method for a true-time-delay array processing (BEAMTAP) algorithm for an optical beamformer by use of a photorefractive crystal. The optical system consists of a tapped-delay line implemented with an acoustooptic Bragg cell, an accumulating scrolling time-delay detector achieved with a traveling-fringes detector, and a photorefractive crystal to store the adaptive spatio-temporal weights as volume holographic gratings. In this analysis, linear shift-invariant integral operators are used to describe the propagation, interference, grating accumulation, and volume holographic diffraction of the spatio-temporally modulated optical fields in the system to compute the adaptive array processing operation.
View Article and Find Full Text PDFProblem: To determine the effect of ovarian stimulation on TH1, TH2 and natural killer (NK) lymphocytes, plasma cytokines, leptin and nitrite levels.
Methods: Women with reproductive failure were studied during the implantation window, at baseline (n = 18) and under ovarian stimulation (gonadotropins + progesterone, n = 6).
Controls: eight fertile women.
Acquired and inherited thrombophilia are associated with recurrent pregnancy loss (RPL). Antithrombotic therapy could restore hemostatic balance and improve early placentation and gestational outcome. We evaluated the efficacy of enoxaparin adapted to the fertility program for prevention of pregnancy loss in 35 women (W) with early RPL and thrombophilia.
View Article and Find Full Text PDFThe fibrinolytic system is involved in blood clot lysis and in other biological processes that require extracellular proteolysis such as ovulation, blastocyst implantation and trophoblastic invasion. An impaired fibrinolytic capacity is a common feature in women suffering from unexplained early recurrent pregnancy loss. We carried out a prospective study with 114 patients.
View Article and Find Full Text PDFWe demonstrate a method of simultaneous holographic recording and readout in photorefractive crystals that provides high write-read beam isolation and wide angular bandwidth. The method uses orthogonally polarized read and write beams and parallel tangent diffraction geometry near the equal curvature condition to provide spatially separable, orthogonally polarized diffracted output beams with high isolation and wide Bragg-matched angular bandwidth. The available angular bandwidth of this read-write technique is analyzed, simulated, and experimentally investigated.
View Article and Find Full Text PDFAn adaptive null-steering phased-array optical processor that utilizes a photorefractive crystal to time integrate the adaptive weights and null out correlated jammers is described. This is a beam-steering processor in which the temporal waveform of the desired signal is known but the look direction is not. The processor computes the angle(s) of arrival of the desired signal and steers the array to look in that direction while rotating the nulls of the antenna pattern toward any narrow-band jammers that may be present.
View Article and Find Full Text PDFPreeclampsia is a disease which appears only during pregnancy. It is highly widespread, and in the underdeveloped countries is the leading cause of maternal mortality. Nowadays it is considered a disease originated in the activation of the vascular endothelium triggered by placental ischemia.
View Article and Find Full Text PDFDiabetes Res Clin Pract
May 1988
We have examined the effect of glipizide, a hypoglycemic sulfonylurea, upon transglutaminase activity in human red blood cells. In a first series of experiments the in vitro effect of the drug was assessed. The results obtained showed that glipizide inhibits transglutaminase activity in human red blood cells.
View Article and Find Full Text PDFFive obese patients were studied during 7 days, 750 mg of tolbutamide, per os, was given. Blood samples were drawn at basal state and at 3, 5, 7 days during the treatment and 6 days after it. The values of transglutaminase activity (that in the basal state were similar to that in the controls) decreased significantly at the seventh day of treatment (72.
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