Electrophysiologic evaluation of facial nerve functions after oxaliplatin treatment.

Purpose: This study analyzes the effect of oxaliplatin treatment on the facial nerve. The facial nerve is the most commonly paralyzed cranial motor nerve because it advances through a long, curved bone canal. Electroneurography and blink reflex are the electrophysiological measurements used for evaluating facial nerve function.

Sudden hearing loss: an effectivity comparison of intratympanic and systemic steroid treatments.

Corticosteroid treatment has been considered the most effective treatment modality for sudden sensorineural hearing loss so far. Application route of corticosteroids may vary. We have designed a prospective randomized case-controlled clinical trial to evaluate the effectivenesses of the different application routes of steroids in the treatment of SSHL.

Long-term Results of ABI in Children With Severe Inner Ear Malformations.

Objective: To report the long-term outcomes of children who received auditory brainstem implant (ABI) because of severe inner ear malformations.

Study Design: Retrospective chart review.

Setting: Tertiary referral otolaryngology clinic.

Comparison of various bone cement ossiculoplasty techniques and functional results.

Objective: In this study, functional results of different bone cement ossiculoplasty techniques are compared.

Methods: Retrospective case review at a tertiary referral center. Patients who underwent middle ear surgery and bone cement ossiculoplasty between 2006-2012 were included.

Prognostic Factors in Sudden Sensorineural Hearing Loss.

Background: Sudden sensorineural hearing loss (SSNHL) is still a complex and challenging process which requires clinical evidence regarding its etiology, treatment and prognostic factors. Therefore, determination of prognostic factors might aid in the selection of proper treatment modality.

Aims: The aim of this study is to analyze whether there is correlation between SSNHL outcomes and (1) systemic steroid therapy, (2) time gap between onset of symptoms and initiation of therapy and (3) audiological pattern of hearing loss.

Early computed tomography findings of the inner ear after stapes surgery and its clinical correlations.

Objective: Pneumolabyrinth resulting from temporal bone trauma and stapes luxation has been associated with sensorineural hearing loss (SNHL). The principal purpose of this study was to determine the incidence and volume of pneumolabyrinth after stapedotomy in which iatrogenic perilymphatic fistula is created and to also correlate this with possible hearing loss and vertigo.

Study Design: Prospective study.

Primary intracranial myxoma of the lateral skull base: a rare entity in clinical practice.

Myxomas are rare benign tumors arising from mesenchymal tissues throughout the body. These tumors are usually seen in the atrium of the heart and the jawbone. Involvement of the skull base with intracranial extension is extremely rare, and only a few cases of primary intracranial myxomas have been described in the literature.

Preliminary results of auditory brainstem implantation in prelingually deaf children with inner ear malformations including severe stenosis of the cochlear aperture and aplasia of the cochlear nerve.

Objective: The aim of our study is to present the results of 11 children where auditory brainstem implantation (ABI) was successfully performed to restore hearing.

Study Design: Case presentation. This study was conducted at the departments of Otolaryngology and Neurosurgery at Hacettepe University Ankara, Turkey.

Bony sheathed chorda tympani: a unique case of incudomalleolar fixation.

Objective: To describe a unilateral conductive hearing loss caused by restriction of the movements of malleus and incus due to chorda tympani in a bony sheath.

Patient: A 23-year-old man with a stable mild conductive hearing loss in the left ear and mild sensorineural hearing loss in the right ear.

Intervention: An exploratory tympanotomy was performed.

Surgical results of cochlear implantation in malformed cochlea.

Objective: To report the surgical aspects of cochlear implantation in malformed cochlea.

Setting: Tertiary care center.

Study Design: Retrospective case review.

Results after revision stapedectomy with malleus grip prosthesis.

Revision stapedectomy with a malleus grip prosthesis is a technically challenging otologic procedure. The prosthesis is usually longer and extends deeper into the vestibule than a conventional stapes prosthesis, creating the potential to affect the vestibular sense organs. The prosthesis also bypasses the ossicular joints, which are thought to play a role in protecting the inner ear from large changes in static pressure within the middle ear.

Pneumolabyrinth following traumatic luxation of the stapes into the vestibule.

Pneumolabyrinth can result from traumatic luxation of stapes into the vestibule. The diagnosis of stapes luxation following a head injury can be delayed especially if the otoscopic examination is within normal limits. Here a 15-year-old girl presenting with vertigo and nystagmus following a blunt head injury was presented, whose computerized tomography revealed air in the vestibule and cochlea (pneumolabyrinth) and stapes was found to be luxated into the vestibule.

c-myc and bcl-2 Expression in supraglottic squamous cell carcinoma of the larynx.

Objectives: To evaluate the expression and prognostic significance of c-myc and bcl-2 oncogenes in squamous cell carcinoma (SCC) of the supraglottic larynx. Study design A retrospective cohort study of 61 patients who underwent surgery for SCC of the supraglottic larynx. Gender, age, TNM status, operative procedure, recurrences, and disease-free survival periods were recorded.

Use of homograft dehydrated temporal fascia in tympanoplasty.

Objective: To investigate the results of myringoplasty operations using homograft dehydrated fascia temporalis (Tutoplast) and compare these with those performed with autograft fascia temporalis.

Study Design: Prospective cohort.

Setting: University hospital.

Necrotizing sialometaplasia of parotid gland: a possible vasculitic cause.

Necrotizing sialometaplasia at the parotid gland location is rare and simulates malignant disease. If it is seen at this location, the causes may be previous dental or parotid gland surgical procedures, which result in blood vessel injuries and thrombosis. We report a parotid gland necrotizing sialometaplasia of a 17-year-old girl, possibly caused by primary vascular damage or vasculitis.

Prognostic value of CD44 variant 6 in laryngeal epidermoid carcinomas.

Background: CD44 variant exon 6 (v6) belongs to a family of transmembrane glycoproteins involved in cell adhesion.

Objectives: To determine the prognostic role of CD44v6 in laryngeal cancer and to examine its relation with other clinicopathologic prognostic factors.

Design: A retrospective cohort study was designed with 93 laryngeal cancer cases.