Publications by authors named "Saroya S"
Article Synopsis
- The study examines the rising rates of early onset colorectal cancer (EOCRC) among African American patients, highlighting significant differences between EOCRC (<45 years) and late-onset colorectal cancer (LOCRC) (>45 years) in terms of demographics and clinical presentation.
- It found that EOCRC cases increased from just over 6% to over 13% of total CRC cases since 2010, with a higher family history of CRC and different symptom profiles, such as more abdominal pain and changes in bowel habits.
- The study also noted that EOCRC patients had a higher rate of metastasis at diagnosis and took longer to undergo surgery compared to LOCRC patients.
Inflammatory bowel disease (IBD) is a chronic inflammatory illness of the gastrointestinal tract (GI), characterized by recurrent episodes of inflammation and tissue destruction. It affects an increasing number of individuals worldwide who suffer from Crohn's disease (CD) or ulcerative colitis (UC). Despite substantial advances in understanding the underlying causes of IBD, the available treatments remain restricted and are sometimes accompanied by severe consequences.
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- This study investigates the health outcomes of COVID-19 patients with a history of cancer compared to those without cancer in the US.
- Among 1,943 COVID-19 patients analyzed, 18.7% had a history of cancer, with a significant portion being African American.
- Findings show that cancer patients experienced longer hospital stays and higher mortality rates, with risk factors for death including male sex, older age, and specific health markers.
- Early identification of these risk factors can aid in improving treatment strategies for better patient outcomes.
Background: Military and veteran populations are unique in their trauma exposures, rates of mental illness and comorbidities, and response to treatments. While reviews have suggested that internet-based Cognitive Behavioral Therapy (iCBT) can be useful for treating mental health conditions, the extent to which they may be appropriate for military and veteran populations remain unclear. The goals of the current meta-analysis are to: (1) substantiate the effects of iCBT for military and veteran populations, (2) evaluate its effectiveness compared to control conditions, and (3) examine potential factors that may influence their effectiveness.
View Article and Find Full Text PDFA shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases.
Proc Natl Acad Sci U S A
October 2021
The mechanism by which molecular oxygen is activated by the organic cofactor pyridoxal phosphate (PLP) for oxidation reactions remains poorly understood. Recent work has identified arginine oxidases that catalyze desaturation or hydroxylation reactions. Here, we investigate a desaturase from the indolmycin pathway.
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