Publications by authors named "Sarode G"

Background: Bibliometric analysis of highly cited papers in a particular discipline brings forward the impactful papers published, the significant journals and the researchers in the field. These studies help in identifying research trends and research lacunae in the field, thus guiding the future research works. Oral proliferative verrucous leukoplakia (OPVL) is a challenging lesion with no uniform diagnostic criteria.

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Background: It is a well-recognized fact that abnormal cell proliferation plays a crucial role in the development of odontogenic lesions. p53 is a tumour-suppressor gene which assists in cell cycle regulation and p63 is a homolog of p53 responsible for ectodermal differentiation and maintenance of stratified epithelial progenitor-cell. Analysing the tissue expression of p53 and p63 in odontogenic lesions may provide us with an insight into their potential role in the development of these lesions.

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Oncocytic mucoepidermoid carcinoma (OMEC) is an uncommon variant of mucoepidermoid carcinoma. Histopathologically, it is characterised by the predominance of cells with large polygonal morphology and with an abundance of eosinophilic granules. We present a rare case of OMEC manifested as painless palatal swelling in a 25-year-old young male.

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Article Synopsis
  • The systematic review investigates the prevalence of oral health issues among prisoners, revealing significant problems in this population.
  • After analyzing 12 studies, it was found that 78.42% of inmates suffer from dental caries and face multiple oral health challenges like periodontal disease and the need for various dental procedures.
  • The study emphasizes the critical need for improved oral health interventions in prisons to address these widespread issues.
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Article Synopsis
  • - Oral submucous fibrosis (OSF) is a condition linked to excessive tissue healing from trauma, primarily caused by areca nut consumption, which can lead to cancerous developments, highlighting the need for better understanding of its causes and effects.
  • - Areca nut triggers fibrosis by increasing inflammatory cytokines and converting fibroblasts into myofibroblasts, resulting in excessive collagen production, further exacerbated by arecoline that boosts harmful substances and activates specific pathways.
  • - The authors suggest redefining OSF as "Areca nut-induced oral fibrosis" (AIOF) to better reflect its connection with areca nut, aiming for improved prevention and treatment approaches by clarifying the condition's unique characteristics and mechanisms.*
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Background: Tobacco is one of the main etiological factors for oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD). CYP1B1 is an enzyme which plays a major role in the phase I detoxification of tobacco, the byproducts of which are subsequently detoxified by phase II enzymes Glutathione S Transferase (GST). We attempted to evaluate the L432V polymorphism and tissue expression of CYP1B1, along with the oxidant-antioxidant status in OSCC progression model.

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Objective: Bibliometric analysis of highly cited papers facilitates researchers in formulating strategic research possibilities and addressing gaps in specific domains. In this context, a bibliometric analysis was conducted to identify published papers on "oral mucosal lesions in COVID-19" within medical literature.

Methods: A comprehensive search was performed in the Scopus database in July 2023.

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Hepatic inflammation is commonly identified in Wilson disease (WD), a genetic disease of hepatic and brain copper accumulation. Copper accumulation is associated with increased oxidative stress and reactive oxygen species generation which may result in non-enzymatic oxidation of membrane-bound polyunsaturated fatty acids (PUFA). PUFA can be oxidized enzymatically via lipoxygenases (LOX), cyclooxygenases (COX), and cytochrome P450 monooxygenases (CYP).

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Background: Metastasizing Ameloblastoma (MA) is an aggressive variant of ameloblastoma (AM) with the ability to metastasize without cytological malignant changes. Thus it aims to comprehensively review the clinico-pathological and prognostic aspects of MA through integration of current literature.

Methods: Electronic searches were conducted in PubMed-MEDLINE, Scopus, Web of Science and Google Scholar.

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