Effects of probiotics on pancreatic inflammation and intestinal integrity in mice with acute pancreatitis.

Background: Severe acute pancreatitis is a potentially life-threatening disease. Despite being a common disorder, acute pancreatitis lacks a specific treatment. The present study aimed to examine the effects of probiotics on pancreatic inflammation and intestinal integrity in mice with acute pancreatitis.

Asynchronous online lecture may not be an effective method in teaching cardiovascular physiology during the COVID-19 pandemic.

Background: Asynchronous online lecture has become a common teaching method in medical education, especially during the COVID-19 pandemic. However, the effectiveness and students' attitudes towards this method under this special circumstance have not been exclusively studied. Hence, we aimed to evaluate these aspects of cardiovascular physiology teaching in an undergraduate medical curriculum.

Huge cutaneous abscess and severe symptomatic hypercalcaemia secondary to infection in an immunocompetent patient.

is among the most common non-tuberculous mycobacteria causing human infections. Apart from pulmonary infection, the most common infection caused by is skin and soft tissue infection, and it is very rare in immunocompetent people. In this report, we present a case of a huge cutaneous abscess caused by A 63-year-old man living in Bangkok presented with progressive pain at the left lateral chest wall for 3 weeks and altered mentation for a few days.

MCM-2, Ki-67, and EGFR downregulated expression levels in advanced stage laryngeal squamous cell carcinoma.

We present the conceptual study investigated the capacity of minichromosome maintenance-2 (MCM-2), Ki-67, and epidermal growth factor receptor (EGFR) to assess the severity and progression of laryngeal squamous cell carcinoma (LSCC) disease and to study the correlations among these markers. A total of 30 patients with LSCC with immunohistochemistry (IHC) staining for MCM-2, Ki-67 and EGFR were examined. Mean expression levels of the three markers were evaluated for comparing between early and advanced stages of LSCC.

Two-dimensional integration approach to teaching cardiovascular physiology: effectiveness and students' perspectives.

Background: Pre-clerkship medical curriculums consist of a series of organ system-based courses and lectures but often lack an integration between organ systems. Such integration could be beneficial for clerkship years and students' future career. Hence, we aimed to share our process of organising an integrative teaching approach in a large class of pre-clerkship medical students and to reflect the students' perspective toward the teaching process in this observational study.

EGFR cut-off point for prognostic impact in laryngeal squamous cell carcinoma.

Various molecular biomarkers, including epidermal growth factor receptor (EGFR), have gained importance as predictors of head and neck cancer disease progression. This study aimed to investigate the ability of EGFR expression as a prognostic marker for laryngeal squamous cell carcinoma (LSCC). A total of 31 patients with LSCC with immunohistochemistry (IHC) staining for EGFR were examined.

Genistein-attenuated Gastric Injury on Indomethacin-induced Gastropathy in Rats.

Objectives: To investigates the mucoprotective effect of genistein on gastric injury in rats with indomethacin (IMN)-induced gastropathy.

Methods: Male Sprague-Dawley rats were randomly divided into three groups. Group 1 (control; = 6) was given distilled water (DW).