Frequent Immunohistochemical Expression of Transcriptional Repressor GATA Binding 1 in Salivary Gland Neoplasms: A Sensitive but Nonspecific Marker.

Context.—: Salivary gland (SG) neoplasms (SGNs) display considerable immunophenotypic diversity. A significant proportion of SG carcinomas develop metastases, with increased diagnostic difficulty at metastatic sites.

Fluorescence in situ hybridization for ETV6 gene rearrangements on destained cytological smears: Role in diagnosis of secretory carcinoma of salivary gland.

Background: Fine-needle aspiration cytology (FNAC) is the first-line diagnostic procedure for salivary gland masses. Secretory carcinoma (SC) is characterized by ETV6 and RET rearrangements detected by fluorescence in situ hybridization (FISH) or reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded and fresh-frozen tissue, respectively. The authors performed FISH on cytological material to assess its role in the diagnosis of SC.

Correlation between radial and femoral arterial blood pressure during reperfusion in living donor liver transplantation.

Background And Aims: Accurate blood pressure measurements are the mainstay for the efficient management of abrupt cardiovascular changes during reperfusion in liver transplant. We sought to compare the femoral and radial pressures during reperfusion and at baseline, 1 h in dissection: portosystemic shunt, reperfusion, at bile duct anastomosis.

Methods: A retrospective study was performed amongst 102 adult patients who underwent R lobe living donor liver transplantation.

Nutritional Interventions and Considerations for the Development of Low Calorie or Sugar Free Foods.

Diabetes is a globally prevalent chronic metabolic disease characterized by blood glucose levels higher than the normal levels. Sugar, a common constituent of diet, is also a major factor often responsible for elevating the glucose level in diabetic patients. However, diabetic patients are more prone to eat sweets amongst the human population.

BrAPI-an application programming interface for plant breeding applications.

Motivation: Modern genomic breeding methods rely heavily on very large amounts of phenotyping and genotyping data, presenting new challenges in effective data management and integration. Recently, the size and complexity of datasets have increased significantly, with the result that data are often stored on multiple systems. As analyses of interest increasingly require aggregation of datasets from diverse sources, data exchange between disparate systems becomes a challenge.

Antioxidant and antimicrobial potential of selected varieties of Piper betle L. (Betel leaf).

Piper betle L., is an evergreen perennial creeper belonging to family Piperaceae and is known to possess numerous medicinal properties. Current study focuses on evaluating antioxidant and antimicrobial potential of betel leaf.

Absolute coronary risk analyser--a tool for managing coronary heart disease risk.

Objectives: The aim of the present study was to develop a coronary risk analyser which can calculate authentically the absolute coronary risk of an individual for coronary risk management.

Methods And Results: After extensive literature survey was done to derive the most appropriate method to calculate the absolute coronary risk. Joint British recommendations derived from Framingham's heart study were adopted for its supreme sensitivity and specificity.

CORONARY RISK ANALYSIS - A STITCH IN TIME.

Coronary heart disease (CHD) is the major cause of sudden death amongst adults throughout the globe. Though the prevalence of CHD is increasing steadily all over, CHD amongst Indians is peculiar in the sense that it is more prevalent, more severe and appears at younger age. Development of CHD depends upon the status of various coronary risk factors in one's body.

Long-term effect of diethylcarbamazine citrate on microfilaraemia status in treated individuals.

Follow up of microfilaraemic individuals infected with Wuchereria bancrofti at five years after treatment was carried out in a tea workers population. Diethylcarbamazine citrate in the dose schedule of 72 mg/kg body weight given in equal daily doses over a period of 21 days cleared 51.6 per cent microfilaraemic individuals five year post-treatment.

Effect of hemoglobin on the growth of mycobacteria and the production of siderophores.

Hemoglobin is known to support the growth of several bacterial species. The growth and the production of siderophores by 4 strains of mycobacteria in the presence of hemoglobin was studied in vitro. The findings were compared with those obtained in the presence of equivalent concentrations of iron in the medium.

Sixth nerve palsy following dental anaesthesia.

A case of sixth nerve palsy following dental anaesthesia given for tooth extraction is reported.

MEDICINAL PLANT WEALTH OF ANDHRA PRADESH - Part II.

In this second part of the study an alphabetical checklist of 211 medicinal plants not covered in the enumeration together with a bibliography is presented here.

Medicinal plant wealth of andhra pradesh - part I.

This paper presents the Medical Plant Wealth of Andhra Pradesh based on the results of Medico - Ethno - Botanical exploration undertaken during the last fourteen years (1971 - 72 till the end of 1984). In all, 117 well known medicinal plants widely used in Ayurveda, Siddha and other systems of Medicine are enumerated here.

Interferon-gamma suppresses B cell stimulation factor (BSF-1) induction of class II MHC determinants on B cells.

The data presented in this manuscript extend our previous observations that recombinant interferon-gamma (reIFN-gamma) can suppress anti-immunoglobulin (anti-Ig)-stimulated B cell proliferation, and demonstrate that reIFN-gamma can also suppress B cell stimulation factor type 1 (BSF-1)-stimulated increases in expression of MHC class II molecules (Ia) on B cells. This suppression is most effective when relatively low concentrations of BSF-1 are employed, but is still very substantial even when optimal concentrations of BSF-1 were used. This suppression is also observed when size-separated small B cells which are devoid of detectable macrophages or NK cells are cultured with BSF-1 and reIFN-gamma, thus suggesting that IFN-gamma-mediated inhibition is a consequence of a direct effect on the B cells.

Recombinant interferon-gamma inhibits the B cell proliferative response stimulated by soluble but not by Sepharose-bound anti-immunoglobulin antibody.

Recombinant-derived interferon-gamma (reIFN-gamma) was found to inhibit B cell proliferation that was stimulated by soluble goat anti-mouse IgD or goat anti-mouse IgM antibodies, but not that stimulated by Sepharose-bound anti-Ig antibodies. Recombinant IFN-gamma also inhibited the BSF-1-enhanced soluble anti-Ig B cell proliferation but did not block BSF-1 enhancement of Sepharose anti-Ig-stimulated B cell DNA synthesis. Recombinant IFN-gamma concentrations as low as 0.

Non-specific cytotoxic cells generated in vitro in response to a weakly immunogenic murine adenocarcinoma. In vivo correlations.

Tumor 85 adenocarcinoma cells, which are very weakly immunogenic for C3H/HeN (C3H) mice, provide a model tumor system for studying the parameters of induction of a cell-mediated immune response which does not appear to be a traditional cytotoxic T-cell or NK-cell response. Mice pre-immunized with irradiated tumor 85 cells are protected about 50% of the time from a challenge of viable tumor 85 cells although it is never possible to protect 100% of the immunized mice. Optimal protection is observed in mice immunized with 10(6) irradiated tumor 85 cells 14 days prior to challenge.