Myocardial infarction area quantification using high-resolution SPECT images in rats.

Background: Imaging techniques enable in vivo sequential assessment of the morphology and function of animal organs in experimental models. We developed a device for high-resolution single photon emission computed tomography (SPECT) imaging based on an adapted pinhole collimator.

Objective: To determine the accuracy of this system for quantification of myocardial infarct area in rats.