Soil-transmitted helminths (STHs) are the most common intestinal parasites infecting humans worldwide. STH infections are a major cause of morbidity and disability. Accurate diagnostic tools are pivotal for assessing the exact prevalence of parasitic infections.
View Article and Find Full Text PDFStrongyloidiasis, caused by infection, is an important neglected tropical disease that causes significant public health problems in the tropics and subtropics. The disease can persist in hosts for decades and may be life-threatening because of hyperinfection and dissemination. Ivermectin (mostly) and albendazole are the most common anthelmintics used for treatment.
View Article and Find Full Text PDFLymphatic filariasis, caused by lymphatic filarial parasites, and , causes significant morbidity and disability to 120 million people in the tropics and subtropics. Chitin has an important role for embryogenesis in adult worms and is a component of microfilaria sheath. Human chitotriosidase (CHIT1) is a chitin-degrading enzyme which provides a protective role against chitin-containing pathogens.
View Article and Find Full Text PDFspp. is one of the most common protozoa of humans and animals worldwide. The genetic diversity of spp.
View Article and Find Full Text PDFStrongyloidiasis is life-threatening disease which is mainly caused by infection. Autoinfection of the parasite results in long-lasting infection and fatal conditions, hyperinfection and dissemination (primarily in immunosuppressed hosts). However, mechanisms of autoinfection and biology remain largely unknown.
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