Publications by authors named "Sarina Heinemann"
Article Synopsis
- Scientists studied tiny particles called extracellular vesicles (EVs) in the blood of glioblastoma patients to see if they could help doctors know more about the disease.
- They found that glioblastoma patients had a lot more EVs in their blood than healthy people, and more EVs meant a shorter survival time for patients.
- The amount of EVs changed after surgery and could even show when a patient's tumor was getting worse before doctors could see it on scans.
Rhizochalinin (Rhiz) is a recently discovered cytotoxic sphingolipid synthesized from the marine natural compound rhizochalin. Previously, Rhiz demonstrated high in vitro and in vivo efficacy in various cancer models. Here, we report Rhiz to be highly active in human glioblastoma cell lines as well as in patient-derived glioma-stem like neurosphere models.
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