Publications by authors named "Saria Almarzook"

The Y chromosome carries information about the demography of paternal lineages, and thus, can prove invaluable for retracing both the evolutionary trajectory of wild animals and the breeding history of domesticates. In horses, the Y chromosome shows a limited, but highly informative, sequence diversity, supporting the increasing breeding influence of Oriental lineages during the last 1500 years. Here, we augment the primary horse Y-phylogeny, which is currently mainly based on modern horse breeds of economic interest, with haplotypes (HT) segregating in remote horse populations around the world.

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The Y chromosome is a valuable genetic marker for studying the origin and influence of paternal lineages in populations. In this study, we conducted Y-chromosomal lineage-tracing in Arabian horses. First, we resolved a Y haplotype phylogeny based on the next generation sequencing data of 157 males from several breeds.

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Article Synopsis
  • Genetic disorders in horses often lead to high fatality rates and economic losses for owners and breeders.
  • A study analyzed 177 Arabian, Barb, and Arab-Barb horses from the MENA region, using advanced genetic sequencing techniques to identify significant genetic disorders.
  • Findings revealed that while the population was free of Lavender Foal Syndrome, 15 horses carried genetic disorders like Cerebellar Abiotrophy and Severe Combined Immunodeficiency, emphasizing the need for genetic testing in these breeds to prevent the spread of harmful variants.
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