A biosensor integrating the electrochemical and fluorescence strategies for detection of aflatoxin B1 based on a dual-functionalized platform.

Background: Aflatoxin B1 (AFB1), is a potent hepatic carcinogen which causes cancer by inducing DNA changes in the liver cells. Variety of methods have been developed for detection of AFB1 which are based on single mode detection strategy. Fabrication of novel platform which are compatible for multimodal detection of AFB1 provide robust performance for reliable detection of AFB1.

Highly sensitive voltammetric determination of NADH based on N-CQDs decorated SnO/ionic liquid/carbon paste electrode.

A highly sensitive and selective modified electrode was successfully developed for the monitoring of nicotinamide adenine dinucleotide (NADH) in the presence of folic acid. In this regard, a carbon paste electrode (CPE) was functionalized by the nitrogen-doped carbon quantum dots/tin oxide (N-CQDs/SnO) nanocomposite and 1-butyl-2,3-dimethyl imidazolium hexafluorophosphate ([CDMIM][PF]) ionic liquid (IL). The structure and surface morphology of the nanocomposite were characterized by various methods, including field emission scanning electron microscopy, energy dispersive spectroscopy (EDS), high-resolution transmission electron microscopy (HR-TEM), and x-ray diffraction (XRD).