Significant Missed Polyps in the UK Bowel Cancer Screening Programme (BCSP): A Retrospective Analysis of Prevalence and Contributing Factors.

Background Colorectal cancer (CRC) remains a significant public health challenge. Patients having abnormal faecal immunochemical test (FIT) results are offered a colonoscopy. The effectiveness of colonoscopies can, however, often be challenged by the occurrence of missed polyps.

Inferior alveolar nerve block anesthesia in children: The effect of ibuprofen and phentolamine mesylate on pain perception.

Context: For successfully managing pediatric dental patients, local anesthesia is essential to eliminate pain during or after the operative period. An early recovery from soft-tissue anesthesia after an inferior alveolar nerve block (IANB) should benefit a young child patient by avoiding the risk of inadvertently biting the soft tissues.

Aims: Hence, the purpose of the study was to (1) evaluate and compare the efficacy of pre- and postoperative ibuprofen on pain perception in children who undergo IANB anesthesia with or without the use of PM and (2) evaluate the average time required for reversal of anesthesia symptoms using phentolamine mesylate.

Indigenous cattle of Sri Lanka: Genetic and phylogeographic relationship with Zebu of Indus Valley and South Indian origin.

The present study reports the population structure, genetic admixture and phylogeography of cattle breeds of Sri Lanka viz. Batu Harak, Thawalam and White cattle. Moderately high level of genetic diversity was observed in all the three Sri Lankan zebu cattle breeds.

Exposure to high thermal conditions for a long time induces apoptosis and decreases total RNA concentration in peripheral blood mononuclear cells among Indian Zebu-Jersey crossbreds.

Background And Aim: Global warming has grave consequences on livestock production systems and profound negative effects on animal production. This study aimed to carry out an thermal stress stimulation (TSS) of bovine peripheral blood mononuclear cells (PBMCs) using different thermal assault conditions (TACs), including normal to extreme temperatures and varying durations of thermal exposure (DTE) to understand how PBMCs of Indian Zebu-Jersey crossbreds respond to various levels and durations of heat shock.

Materials And Methods: Ten milliliters of blood were collected from 70 Indian Zebu-Jersey crossbreds under aseptic conditions and were sampled for isolating PBMCs.

Assessment of Mutation Drift Equilibrium and the Occurrence of a Recent Genetic Bottleneck in South Indian Zebu Cattle.

During the last few decades, the effective population size of indigenous zebu cattle breeds has declined drastically, resulting in the classification of some of them into the vulnerable, endangered, or critically endangered category. Drastic reductions in the effective size of a population may result in genetic bottlenecks and can affect within-breed genetic variability and its viability. The present study was undertaken with the objective of evaluating South Indian zebu cattle populations for mutation drift equilibrium and to detect the occurrence of recent genetic bottleneck events.

Hybrid optimization model for conjunctive use of surface and groundwater resources in water deficit irrigation system.

The increasing demand for food production with limited available water resources poses a threat to agricultural activities. Conventional optimization algorithms increase the processing stage and perform in the space allocated from user. Therefore, the proposed work was used to design better performance results.

Single nucleotide polymorphism in STAT5A could not endorse variation in milk production traits in Indian bovine population.

The Signal Transducer and Activator of Transcription 5A (STAT5A) gene involved in activating the transcription of milk protein genes was predicted to be influencing milk production traits. The present study was undertaken to investigate the suitability of the polymorphism of STAT5A as a marker for milk traits in Ongole, crossbred cattle and Murrah buffaloes from Southern India. Blood samples (n = 502) for DNA isolation and milk samples (n = 222) from different genetic groups were collected from various farms.

New DRASTIC framework for groundwater vulnerability assessment: bivariate and multi-criteria decision-making approach coupled with metaheuristic algorithm.

Unplanned anthropogenic activities and erratic climate events pose serious threats to groundwater contamination. Therefore, the vulnerability assessment model becomes an essential tool for proper planning and protection of this precious resource. DRASTIC is an extensively adopted groundwater vulnerability assessment model that suffers from several shortcomings in its assessment due to the subjectivity of its rates and weights.

Legacy of draught cattle breeds of South India: Insights into population structure, genetic admixture and maternal origin.

The present study is the first comprehensive report on diversity, population structure, genetic admixture and mitochondrial DNA variation in South Indian draught type zebu cattle. The diversity of South Indian cattle was moderately high. A significantly strong negative correlation coefficient of -0.

Molar Protraction Using Miniscrews (Temporary Anchorage Device) with Simultaneous Correction of Lateral Crossbite: An Orthodontic Case Report.

Early loss of permanent teeth, congenitally missing lateral incisors or second premolars, extremely displaced or impacted canines, all result in a reduced upper dentition. That leads to the development of crossbite in the maxillary dentition. Partial denture prosthesis, dental implants, and space closure by fixed orthodontics are the various means of treating the edentulous spaces.

Effect of Simplifying Drilling Technique on Heat Generation During Osteotomy Preparation for Dental Implant.

Objectives: To test the hypothesis that there would be no difference in heat production by reducing the number of drills during the implant site preparation relative to conventional drilling sequence.

Methods: A total of 120 implant site preparations with 3 different diameters (3.6, 4.

Candidate gene approach for parasite resistance in sheep--variation in immune pathway genes and association with fecal egg count.

Sheep chromosome 3 (Oar3) has the largest number of QTLs reported to be significantly associated with resistance to gastro-intestinal nematodes. This study aimed to identify single nucleotide polymorphisms (SNPs) within candidate genes located in sheep chromosome 3 as well as genes involved in major immune pathways. A total of 41 SNPs were identified across 38 candidate genes in a panel of unrelated sheep and genotyped in 713 animals belonging to 22 breeds across Asia, Europe and South America.

Two-year impacts on employment and income among adults receiving antiretroviral therapy in Tamil Nadu, India: a cohort study.

Objectives: to estimate the economic impact of antiretroviral therapy (ART) on employment and income of treated patients as well as a comparison group of pre-ART patients who receive care and support in Tamil Nadu, India.

Methods: a cohort of 1238 HIV-infected patients was followed between 2005 and 2007. Socioeconomic data were collected at 6-month intervals.

Thalidomide for the treatment of chronic gastrointestinal bleeding from angiodysplasias: a case series.

Background: Mucosal angiodysplasias, either inherited or acquired, can cause gastrointestinal bleeding, sometimes refractory to treatment. From earlier case reports, thalidomide has been described to possess some benefits in this disease, but its benefits and risks nevertheless remain unclear.

Objectives: This pilot study assesses the efficacy, safety, and side-effect of thalidomide in the treatment of patients with chronic gastrointestinal bleeding from angiodysplasias.

Unique expression of human papilloma virus type 5 and type 16 in esophageal squamous cell carcinoma-a case report.

The role of human papilloma virus (HPV) in esophageal cancers from the low-incidence area (Western population) is unclear. We report a case of esophageal squamous papillomatosis associated with underlying esophageal squamous cell carcinoma (OSCC). The esophagectomy specimen confirmed presence of HPV-5 and HPV-16 suggesting a viral etiology.

Need for an urgent ultrasound examination for neck lump.

Thromboembolic phenomenon is rare but serious consequence of ovarian hyperstimulation syndrome (OHSS) and in vitro fertilization (IVF) treatment. We present a case of thrombosis of the right internal jugular vein presenting as a neck lump to the ENT department. Ultrasonography of the neck and upper extremity revealed thrombosis of right internal jugular vein.

Transjugular intrahepatic portosystemic stent shunt: 11 years' experience at a regional referral centre.

Objectives: Transjugular intrahepatic portosystemic stent shunt (TIPSS) is now widely used in the treatment of uncontrolled and recurrent variceal haemorrhage. This study reports the outcome and long-term follow-up of 125 patients who were referred to a single centre for TIPSS.

Methods: One hundred and twenty-five patients were referred to undergo TIPSS.