Overactive bladder symptoms in patients undergoing rigid and flexible cystoscopy.

Purpose: To evaluate overactive bladder (OAB) symptoms in patients undergoing diagnostic cystoscopy. Overall changes in the entire study population were assessed, as well as broken down by various subgroups.

Methods: A prospective multi-center study among consecutive 450 adults undergoing diagnostic cystoscopy was conducted.

Association between metabolic syndrome and overactive bladder: a case-control study.

Objective: The aim of this case-control study was to investigate the association between overactive bladder (OAB) and metabolic syndrome (MetS). The primary hypothesis was that OAB is significantly more prevalent among patients with MetS than in control participants.

Materials And Methods: A case-control study was conducted among 114 patients, with 57 patients in the MetS group and 57 in the control group.

Anxiety and depression analyses of patients undergoing diagnostic cystoscopy.

Purpose: To prospectively assess anxiety and depression in patients undergoing diagnostic cystoscopy.

Methods: Patients presenting for outpatient diagnostic cystoscopy were recruited from four European urological departments. Anxiety and depression were assessed with the 'Hospital Anxiety and Depression Scale' (HADS) before cystoscopy and after 1 week.

Prospective, multi-institutional pain assessment of 150 women undergoing diagnostic cystoscopy.

Background: The aim of this study was to prospectively assess women's pain during rigid and flexible diagnostic cystoscopy and afterwards during a one-week follow-up.

Methods: Prospective, multi-institutional trial analyzing numeric rating scales (NRS) of women undergoing diagnostic cystoscopy. Pain categories: no (0 points), mild (1-3), moderate (4-6) and severe pain (7-10).

Prospective multi-institutional study analyzing pain perception of flexible and rigid cystoscopy in men.

Objective: To evaluate pain perception in men undergoing flexible or rigid diagnostic cystoscopy.

Methods: This is a prospective multi-institutional analysis of men undergoing cystoscopy in 4 European departments of urology. Pain perception was assessed with an 11-point numeric rating scale.

Only a minority of patients in the urological emergency unit need urgent urology care.

Objective: To present patients who were examined, monitored and admitted at the urological emergency unit (UEU) at the University Hospital, Split during the summer and winter of 2010 and to establish who of them were really in need of immediate urological care.

Methods: A retrospective study of patients and diagnoses of patients examined at the UEU was undertaken during two winter and two summer months 2010. We compared the total number of patients, the number of patients with urological issues, patients with urological emergencies, patients with non-urological issues, patients who were briefly monitored at the UEU, and patients admitted to the urology department, within these two periods.

Impact of gender on success and complication rates after ureteroscopy.

Purpose: To investigate the impact of gender differences on treatment success, intraoperative and postoperative complications in patients undergoing ureteroscopy (URS).

Materials And Methods: A prospectively maintained database of 927 consecutively performed ureteroscopies on solitary ureteral stones in four different centers was retrospectively analyzed. Stones were detected with preoperative computed tomography scans or intravenous urography imaging.

The interstitial expression of alpha-smooth muscle actin in glomerulonephritis is associated with renal function.

Background: In a healthy kidney, contractile protein alpha-smooth muscle actin (ASMA) is immunohistochemically strongly expressed only in the blood vessels, while in pathological conditions it can be visualized in glomerular mesangial cells and interstitial myofibroblasts. The aim of this study was to explore the possible correlation between expression of ASMA in glomerulonephritis (GN) and indicators of renal function.

Material/methods: We analyzed expression of ASMA in percutaneous renal biopsy of 142 adult and pediatric patients with GN and its correlation with blood pressure, serum creatinine, creatinine clearance and 24-hour urine protein at the time of biopsy.

Increased pulmonary vascular resistance and reduced stroke volume in association with CO2 retention and inferior vena cava dilatation.

Changes in cardiovascular parameters elicited during a maximal breath hold are well described. However, the impact of consecutive maximal breath holds on central hemodynamics in the postapneic period is unknown. Eight trained apnea divers and eight control subjects performed five successive maximal apneas, separated by a 2-min resting interval, with face immersion in cold water.

Long-lasting partial regression of glioblastoma multiforme achieved by edotecarin: case report.

We describe the response to a new chemotherapy agent, topoisomerase I inhibitor edotecarin in an 18-year-old woman with recurring glioblastoma. The therapy was administered for 17 months. The radiological partial response and clinical improvement have been achieved, with minor toxicity.

Effect of human splenic contraction on variation in circulating blood cell counts.

1. The human spleen sequesters 200-250 mL densely packed red blood cells. Up to 50% of this viscous blood is actively expelled into the systemic circulation during strenuous exercise or simulated apnoea (breath-hold) diving.

Concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by consolidation chemotherapy in the treatment of locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri.

The optimal treatment of women with locally advanced adenocarcinoma or adenosquamous carcinoma of the cervix uteri is still undefined. We report a series of four consecutive patients with locally advanced adeno- or adenosquamous carcinomas of the uterine cervix (FIGO Stages IB-IIIB) treated by concomitant chemobrachyradiotherapy with ifosfamide and cisplatin followed by one to four cycles of consolidation chemotherapy with the same drug combination. After completion of this treatment all patients showed complete clinical remission.

The grade of acute thymus involution in neonates correlates with the duration of acute illness and with the percentage of lymphocytes in peripheral blood smear. Pathological study.

In various stressful conditions, the thymus is subjected to incidental involution, mostly due to the thymocytolytic effect of secreted glucocorticosteroids. The aim of this study was to examine acute thymic involution in sick neonates and to compare the morphological grade with some clinical and laboratory parameters. The influence of the illness on thymus tissue was investigated in 100 neonates who were treated and died in a neonatology intensive care unit.