Publications by authors named "Sarath Lal Mannumbeth Renjithal"

Article Synopsis
  • - Left atrial appendage closure (LAAC) helps prevent strokes in patients with atrial fibrillation, but peri-device leak (PDL) might increase the risk of thromboembolic events.
  • - A systematic review of 54,279 patients from 11 studies revealed that PDL significantly raised the odds of experiencing strokes, transient ischemic attacks (TIAs), or systemic embolisms.
  • - Despite the increased risk of thromboembolic events linked to PDL, the study found no significant differences in overall mortality, cardiovascular mortality, or ischemic strokes.
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Unlabelled: Organizing pneumonia (OP) is a form of interstitial lung disease that develops in response to acute lung injury. SARS-CoV-2 causes a wide range of lung and extrapulmonary disease, but there are few data suggesting an association between COVID-19 and OP. We describe a patient with COVID-19 pneumonia who developed severe progressive OP with significant morbidity.

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Background: Left atrial (LA) appendage closure (LAAC) is effective in patients with atrial fibrillation who are not candidates for long-term anticoagulation. However, the impact of LAAC on LA function is unknown. The aim of this study is to evaluate the impact of LAAC on atrial function.

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Article Synopsis
  • Ischemic stroke due to atrial fibrillation can be prevented with anticoagulation, but some patients cannot use oral anticoagulants, making the WATCHMAN device a viable alternative that effectively reduces stroke risk.
  • After the WATCHMAN procedure, patients typically receive warfarin and aspirin for 45 days, followed by adjustments based on follow-up tests, with some patients possibly only needing antiplatelet therapy if they have a high bleeding risk.
  • Current practices often favor a regimen combining warfarin and antiplatelets, but more research is necessary to develop tailored antithrombotic strategies for those at elevated bleeding risk.
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