Publications by authors named "Sarath Gopalakrishnan"

Wearable electronics have become integral for monitoring physiological parameters in diverse applications, particularly in medical and military fields. e-Textiles, featuring integrated conductive threads or fabrics, offer seamless integration and comfort for prolonged contact with the body. Despite their potential, the biofouling of textile-based electrode systems by skin microbes remains a significant challenge, limiting their operational lifespan.

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A substantial number of critically ill patients in intensive care units (ICUs) rely on indwelling urinary catheters (IDCs), demanding regular monitoring of urine bags. This process increases the workload for healthcare providers and elevates the risk of exposure to contagious diseases. Moreover, IDCs are a primary cause of catheter-associated urinary tract infections (UTIs) in ICU patients whose delayed detection can have life-threatening complications.

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Article Synopsis
  • Effective management of Inflammatory Bowel Disease (IBD) relies on regular monitoring of inflammation in the gastrointestinal tract to track disease progression and relapses.
  • A new single-use capsule technology has been developed that measures inflammation at specific GI locations using a pH-sensitive coating and a chemiluminescent sensor for accurate detection of myeloperoxidase (MPO).
  • The system demonstrated high sensitivity and consistency in detecting inflammation in GI fluids from pig models, marking a significant advancement in minimally invasive monitoring for tailored IBD treatment strategies.
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Article Synopsis
  • Inflammatory bowel disease (IBD) is increasingly common, affecting 6.8 million people worldwide, with a high relapse rate of 40% within a year.
  • Traditional endoscopy techniques are limited, relying on subjective image assessments that are not effective for early detection and regular monitoring of IBD.
  • A new miniaturized smart capsule has been developed to monitor reactive oxygen species (ROS) levels, using advanced sensors for location tracking and inflammation detection throughout the gastrointestinal tract, demonstrating promise for improved diagnosis and treatment of digestive diseases.
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For a continuous healthcare or environmental monitoring system, it is essential to reliably sense the analyte concentration reported by electrochemical sensors. However, environmental perturbation, sensor drift, and power-constraint make reliable sensing with wearable and implantable sensors difficult. While most studies focus on improving sensor stability and precision by increasing the system's complexity and cost, we aim to address this challenge using low-cost sensors.

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Contamination of meat with pathogenic microorganisms can cause severe illnesses and food waste, which has significant negative impacts on both general health and the economy. In many cases, the expiration date is not a good indicator of meat freshness as there is a high risk of contamination during handling throughout the supply chain. Many biomarkers, including color, odor, pH, temperature, and volatile compounds, are used to determine spoilage.

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Originally developed for use in controlled laboratory settings, potentiometric ion-selective electrode (ISE) sensors have recently been deployed for continuous, in situ measurement of analyte concentration in agricultural (e.g., nitrate), environmental (e.

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Precision Agriculture (PA) is an integral component of the contemporary agricultural revolution that focuses on enhancing food productivity in proportion to the increasing global population while minimizing resource waste. While the recent advancements in PA, such as the integration of IoT (Internet of Things) sensors, have significantly improved the surveillance of field conditions to achieve high yields, the presence of batteries and electronic chips makes them expensive and non-biodegradable. To address these limitations, for the first time, we have developed a fully Degradable Intelligent Radio Transmitting Sensor (DIRTS) that allows remote sensing of subsoil volumetric water using drone-assisted wireless monitoring.

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