Comparative Evaluation of Surface Roughness and Color Stability of Polyetheretherketone with Conventional Interim Prosthetic Materials: An Study.

Aim: The aim of this study was to compare the surface roughness and color stability of polyetheretherketone (PEEK) with those of conventional interim prosthetic materials like polymethylmethacrylate, bis-acrylic composite, and rubberized diurethane dimethacrylate, following immersion in solutions of varying pH value.

Materials And Methods: A total of 320 circular discs with 10 mm diameter and 2 mm height were divided based on the fabrication ( = 80)-group A: polymethylmethacrylate; group B: bis-acrylic composite; group R: rubberized diurethane; and group P: hot-pressed PEEK-and were subjected to baseline measurement of roughness ( = 40) and color ( = 40) using 3D profilometer and UV-Vis spectrophotometer, respectively. Later, 10 samples from each group were immersed in distilled water, black coffee, green tea, and Pepsi, respectively, for 120 days, and measurements of roughness and color were repeated.

Integration of Three-Dimensional Scanning and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Technology in Routine Prosthodontic Practice: A Cross-Sectional Study in Kerala.

Background: Digital dentistry has transformed all aspects of dentistry, especially prosthodontics, and is increasingly used for diagnosis, treatment planning, execution, student training, and research. This study aimed to assess the perception, attitude, and practice of digital technology in prosthodontics among dental professionals in Kerala, India.

Materials And Methods: A cross-sectional, questionnaire-based study was conducted among dental professionals in Kerala.

Near infrared-emitting multimodal nanosystem for in vitro magnetic hyperthermia of hepatocellular carcinoma and dual imaging of in vivo liver fibrosis.

Prolonged usage of traditional nanomaterials in the biological field has posed several short- and long-term toxicity issues. Over the past few years, smart nanomaterials (SNs) with controlled physical, chemical, and biological features have been synthesized in an effort to allay these challenges. The current study seeks to develop theranostic SNs based on iron oxide to enable simultaneous magnetic hyperthermia and magnetic resonance imaging (MRI), for chronic liver damage like liver fibrosis which is a major risk factor for hepatocellular carcinoma.

Fluorescent carbon dots tailored iron oxide nano hybrid system foroptical imaging of liver fibrosis.

Hybrid nanoparticles are innovative invention of last decade designed to overcome limitations of single-component nanoparticles by introducing multiple functionalities through combining two or more different nanoparticles. In this study, we are reporting development of magneto-fluorescent hybrid nanoparticles by combining iron oxide and carbon nanoparticles to enablefluorescence imaging which also has all the required characteristic properties to use as Magnetic Resonance Imaging (MRI) contrast agent. In order to achieve dual-functional imaging, alginate and pullulan coated super paramagnetic iron oxide nanoparticles (ASPION and PSPION) and Carbon dots (Cdts) were synthesised separately.

The effect of metallic dental restorations and implants in causing patient discomfort and artefacts during magnetic resonance imaging of the head and neck.

Context: Patients with metallic dental objects in their oral cavity are often associated with discomfort or artefacts during magnetic resonance imaging (MRI) of the head and neck.

Aim: This study was conducted to evaluate the effects of metallic dental objects in causing patient discomfort and artefacts during MRI of the head and neck region.

Design: This is an observational study including 538 participants from various specialized MRI centres in Kozhikode.

Retention Strength of Zirconia Crowns Cemented onto PEEK Abutments Using Two Different Types of Resin Cement With or Without Primer Application-An In Vitro Study.

Purpose: To evaluate the retention of zirconia crowns on polyetheretherketone (PEEK) abutments using different luting agents, with and without PEEK primer.

Materials And Methods: A total of 100 PEEK abutment replicas were fabricated, airborne particle-abraded with aluminum oxide, and divided into four groups (n = 25). A total of 100 zirconia crowns were fabricated and cemented using either adhesive resin cement or self-adhesive resin cement with and without PEEK primer; thus, the groups were: group AA-P (adhesive cement with primer); group AA-N (adhesive cement without primer); group SA-P (self-adhesive cement with primer); and group SA-N (self-adhesive cement without primer).

Asialoglycoprotein receptor targeted optical and magnetic resonance imaging and therapy of liver fibrosis using pullulan stabilized multi-functional iron oxide nanoprobe.

Early diagnosis and therapy of liver fibrosis is of utmost importance, especially considering the increased incidence of alcoholic and non-alcoholic liver syndromes. In this work, a systematic study is reported to develop a dual function and biocompatible nanoprobe for liver specific diagnostic and therapeutic applications. A polysaccharide polymer, pullulan stabilized iron oxide nanoparticle (P-SPIONs) enabled high liver specificity via asialogycoprotein receptor mediation.

Randomized clinical trial of zirconia and polyetheretherketone implant abutments for single-tooth implant restorations: A 5-year evaluation.

Statement Of Problem: Titanium-supported polyetheretherketone (PEEK) abutments provide an economic alternative to zirconia abutments in esthetically important areas. Research comparing the performance regarding esthetics, longevity, and biologic parameters of PEEK abutments is lacking.

Purpose: The purpose of this clinical study was to determine whether PEEK implant abutments provide similar esthetic and biologic parameters and survival rates as zirconia implant abutments.

Biosafety of citrate coated zerovalent iron nanoparticles for Magnetic Resonance Angiography.

Though nanoparticles are being used for several biomedical applications, the safety of the same is still a concern. It is very routine procedure to check the preliminary safety aspects of the particles intended for applications. The major tests include how the material reacts to a normal cell, how it behaves with the blood cells and also whether any lysis take place in the presence of these materials.

Fluorescence spectroscopy as an efficient tool for staging the degree of liver fibrosis: an in vivo comparison with MRI.

The study utilizes autofluorescence spectroscopy (AFS) along with multivariate spectral analysis for differentiating various stages of hepatic fibrosis. AFS has recently emerged as an efficient tool for evaluating the variations in different endogenous flurophores. In this study, the potential of AFS for differentiating the stages of liver fibrosis is assessed and compared with the results of enzyme evaluation, histopathology and the most advanced diagnostic tool, MRI.

Multifunctional hybrid nanoconstruct of zerovalent iron and carbon dots for magnetic resonance angiography and optical imaging: An In vivo study.

In magnetic resonance imaging (MRI), gadolinium (Gd) complexes are very often used as contrast agents to enhance the signal from soft tissue deformities and vascular anomalies, to improve the accuracy of diagnosis. The safety concern of using Gd complexes in renally compromised patients pose limitations on its application. To overcome this scenario, we introduce a nontoxic zerovalent iron based nanoparticle as a novel contrast agent for MR angiography and a hybrid version of the same to serve as a dual function contrast agent for targeted liver imaging.

Catechin tuned magnetism of Gd-doped orthovanadate through morphology as T-T MRI contrast agents.

Tetragonal (t)-LaVO has turned out to be a potential host for luminescent materials. Synthesis of t-LaVO till date has been based on chelating effect of EDTA making it not ideal for bioimaging applications. An alternative was proposed by us through the use of catechin.

Total Phenol Content and In Vitro Antioxidant Potential of Helicanthus elastica (Desr.) Danser-A Less-explored Indian Mango Mistletoe.

Natural products are an important source of antioxidant molecules like tannins, phenolic compounds, flavonoids, etc., Helicanthus elastica (Desr.) Danser (Loranthaceae) is one such plant belonging to the category of mistletoe, and grows commonly on the mango trees in India.

Antimicrobial Potential of Helicanthus elastica (Desr.) Danser - A less explored Indian mistletoe Growing on Mango Trees.

Helicanthus elastica (Desr.) Danser (Loranthaceae) is a less-known medicinally important mistletoe species occurring in India. It is used to check abortion, and also in vesical calculi and kidney affections.

Citrate coated iron oxide nanoparticles with enhanced relaxivity for in vivo magnetic resonance imaging of liver fibrosis.

Superparamagnetic iron oxide nanoparticles are widely used for the magnetic resonance imaging (MRI) applications. The surface characteristics, magnetic properties, size and targeting efficiency of the material are crucial factors for using the same as contrast agents. We report a simple synthesis method of citrate coated iron oxide nanoparticles and its systematic characterization.

Synthesis and characterization of dextran stabilized superparamagnetic iron oxide nanoparticles for in vivo MR imaging of liver fibrosis.

The field of medical imaging has recently seen rapid advances in the development of novel agents for enhancing image contrast. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) with a variety of surface properties have been tried as effective contrast agents for magnetic resonance imaging, but with major side effects. In this study, the surface chemistry of SPIONs of size 12 nm was modified with high molecular weight dextran to yield particles of size 50 nm, without compromising the magnetic properties.

Vitiquinolone--a quinolone alkaloid from Hibiscus vitifolius Linn.

Phytochemical investigations of the powdered root of Hibiscus vitifolius Linn. (Malvaceae) was extracted successively with n-hexane and chloroform. Analysis of the n-hexane extract by GC-MS led to the identification of twenty-six components by comparison of their mass spectra with GC-MS library data.

Isolation of methyl 27-caffeoyloxyoleanolate--a new oleanane Triterpenoid from the roots of Hibiscus vitifolius.

A new oleanane triterpenoid, methyl 27-caffeoyloxyoleanolate (2), together with eight known compounds viz. oleanolic acid, kaempferol, quercetin, beta-sitosterol-3-O-beta-D-glucopyranoside, kaempferol-3-O-alpha-D-rhamnopyranoside, gossypin, quercetin-3-O-beta-D-glucopyranoside and mangiferin were isolated from the ethanol extract of roots of Hibiscus vitifolius Linn. The structure of the new compound 2 was elucidated from spectroscopic, ESI-MS and physical data.

Fluorescence spectroscopy as a highly potential single-entity tool to identify chromophores and fluorophores: study on neoplastic human brain lesions.

Fluorescence and diffuse reflectance spectroscopy are powerful tools to differentiate normal and malignant tissue based on the emissions from endogenous fluorophores and diffuse reflection of absorbers such as hemoglobin. However, separate analytical methods are used for the identification of fluorophores and hemoglobin. The estimation of fluorophores and hemoglobin simultaneously using a single technique of autofluorescence spectroscopy is reported, and its diagnostic potential on clinical tissue samples is potentially exploited.

Essential oil constituents of Illicium griffithii and its antimicrobial activity.

The essential oil of the fruit of Illicium griffithii Hook f. et Thoms. was extracted using Clevenger's apparatus.

Quality control standards for the roots of three plumbago species.

Physicochemical parameters of roots of three Plumbago species, Plumbago capensis, P. rosea and P. zeylanica belonging to Plumbaginaceae were analyzed.

Analgesic and Antiinflammatory activity of Amukkarac curanam.

Amukkarac curanam a polyherbal Siddha formulation was examined for its analgesic and antiinflammatory activity at a dose of 500 mg/kg, p.o. The experimental methods used were tail immersion and acetic acid induced writhing method for analgesic and cotton pellet induced granuloma formation for antiinflammatory activity.

Optimum wavelength for the differentiation of brain tumor tissue using autofluorescence spectroscopy.

Objective: The role of autofluorescence spectroscopy in the detection and staging of benign and malignant brain tumors is being investigated in this study, with an additional aim of determining an optimum excitation wavelength for the spectroscopic identification of brain tumors.

Materials And Methods: The present study involves in-vitro autofluorescence monitoring of different human brain tumor samples to assess their spectroscopic properties. The autofluorescence measurement at four different excitation wavelengths 320, 370, 410, and 470 nm, were carried out for five different brain tumor types: glioma, astrocytoma, meningioma, pituitary adenoma, and schwannoma.

Antioxidant, Heavy Metals and Elemental Analysis of Holoptelea integrifolia Planch.

The ethanol crude extract of stem bark of Holoptelea integrifolia Planch. traditionally used in Indian system of medicine was screened for its antioxidant activity using α-tocopherol as standard antioxidant. The free radical scavenging potential of the extract was evaluated by two different antioxidant methods; ferric thiocyanate and thiobarbituric acid method.

Arsenicicoccus bolidensis a novel arsenic reducing actinomycete in contaminated sediments near the Adak mine (northern Sweden): impact on water chemistry.

Weathering of mine tailings in Adak results in high As concentrations in surface and ground water, sediments, and soil. In spite of the oxic conditions, As-rich surface and ground water samples indicate As(III) species predominantly (up to 83%). Several microorganisms were isolated from the enrichment cultures that were involved in As cycling.