Cost of Illness Study on Oral Cancer in Australia.

Objectives: The aim of this study is to estimate the economic burden of oral cancer in Australia from the societal perspective.

Methods: The population consisted of the prevalence of lip and oral cavity cancer, and other lip, oral cavity, and pharynx cancers for ages 40 years and older. Healthcare costs of oral cancer were estimated using 2019-2020 Australian Disease Expenditure Data.

Promoting oral cancer screening by general practitioners in Australia: Strengthening primary healthcare.

Background: Oral cancer remains a significant public health issue. General practitioners (GPs) can play an important role in raising awareness of oral cancer.

Objective: This paper explores why providing advice relating to modifiable risk behaviours associated with oral cancer and undertaking routine oral cancer screening are important for GPs in clinical practice.

"The Ultrathin Parascapular Flap: Proof of Concept and Use in Plantar Foot Reconstruction".

Optimal reconstruction of weight-bearing plantar foot defects is challenging due to the need for relatively thin coverage with simultaneous durability. The medial plantar flap provides an excellent tissue match but is not always available or appropriate (Figure 1, 2). Microsurgical free flap reconstruction provides many options for coverage.

Beyond the Genome: Deciphering the Role of MALAT1 in Breast Cancer Progression.

The MALAT1, a huge non-coding RNA, recently came to light as a multifaceted regulator in the intricate landscape of breast cancer (BC) progression. This review explores the multifaceted functions and molecular interactions of MALAT1, shedding light on its profound implications for understanding BC pathogenesis and advancing therapeutic strategies. The article commences by acknowledging the global impact of BC and the pressing need for insights into its molecular underpinnings.

Identifying the Question Similarity of Regulatory Documents in the Pharmaceutical Industry by Using the Recognizing Question Entailment System: Evaluation Study.

Background: The regulatory affairs (RA) division in a pharmaceutical establishment is the point of contact between regulatory authorities and pharmaceutical companies. They are delegated the crucial and strenuous task of extracting and summarizing relevant information in the most meticulous manner from various search systems. An artificial intelligence (AI)-based intelligent search system that can significantly bring down the manual efforts in the existing processes of the RA department while maintaining and improving the quality of final outcomes is desirable.

Health and Lifestyle Issues among Youth: A Record Analysis of Contributing Factors among Beneficiaries Attending Youth Mental Health Promotion Clinics (Yuva Spandana Kendras) in Karnataka, India.

Background: Youth are consideren to be most vulnerable to health and lifestyle issues (HLS) in India. The current study aims to investigate the factors that contribute to health and lifestyle issues among youth attending mental health promotion clinics (YMHP) in Karnataka.

Method: Three-year first-visit data from beneficiaries (aged 15-35 years) attending YMHP clinics in Karnataka between 2017 and 2020 were analyzed.

A Study to Describe the Pattern of Cutaneous Adverse Effects of COVID-19 Vaccines (Covishield and Covaxin).

Background: Vigorous administration of COVID-19 vaccines to tackle the ongoing pandemic has led to increasing research on adverse effects including both systemic and cutaneous.

Objective: A prospective observational study to delineate the cutaneous adverse effects of two vaccines, namely Covishield and Covaxin, administered in two doses in northern India.

Materials And Methods: The study was conducted in a tertiary hospital in northern India wherein patients were asked to report voluntarily any cutaneous adverse effects after COVID-19 vaccination to the dermatology department.

Recent Progress in the Understanding and Management of Acute Mountain Sickness: A Narrative Review.

Background: Individuals at higher altitudes may experience a decrease in blood oxygen levels, which can result in a variety of clinical illnesses, such as high-altitude pulmonary edema, high-altitude cerebral edema, and milder but more common acute mountain sickness (AMS).

Objective: This study aims to review the current state of knowledge related to motion sickness, the risk of AMS, and pharmacological and non-pharmacological treatments for AMS.

Methods: Several databases, including PubMed, Bentham Science, Elsevier, Springer, and Research Gate, were used to compile the data for the article following a thorough analysis of the various research findings connected to acute mountain sickness and motion sickness, along with treatments and prevention.

Genital ulcers following all-trans-retinoic acid therapy: A case series with review of literature.

All-trans-retinoic acid (ATRA) has transformed the treatment of acute promyelocytic leukemia. Most of the adverse effects associated with this drug are minor barring differentiation syndromes. Genital ulcers feature among the underreported adverse effects of ATRA which needs to be kept in mind to avoid life-threatening complications.

A Detailed Review of Molecular Pathways and Mechanisms Responsible for the Development and Aggravation of Neuropathy and Nephropathy in Diabetes.

Background: Diabetic mellitus is responsible for triggering many conditions, such as neuropathy, nephropathy, and retinopathy. Hyperglycemia leads to the development of oxidative stress conditions, activation of pathways, and generation of metabolites, leading to complications like neuropathy and nephropathy.

Objective: This paper aims to discuss the mechanism of actions, pathways, and metabolites triggered due to the development of neuropathy and nephropathy post-long-haul diabetes in patients.

Knowledge, Attitudes and Practices of Indian Immigrants in Australia towards Oral Cancer and Their Perceived Role of General Practitioners: A Cross-Sectional Study.

Oral cancer is highly prevalent in the Indian subcontinent. With the increasing immigration of Indians to Australia, a potential rise in oral cancer cases can be expected if they continue engaging in oral cancer risk practices. Unfortunately, little is known on this topic in the Australian context.

Scholastic performance and ambitions in retropositive and vulnerable pediatric patients: A prospective study.

Introduction: It is widely recognized that HIV epidemic has a negative impact on retropositive pediatric patients. However, at present, the school performance and ambitions in retropositive and vulnerable pediatric patients from India are lacking.

Aims: The aim of this study was to analyze the possible association between scholastic performance and ambitions in retropositive and vulnerable status in pediatric patients.