The importance of lipid spectrum changes in women with polycystic ovary syndrome(PCOS).

Aim: of the study was to compare levels of blood lipids, anthropometric characteristics and their relationship in women with PCOS with a group of healthy women.

Methods And Results: We determined anthropometric indicators (BMI - body mass index, waist measurement, waist/hip ratio), blood lipid levels (total cholesterol TCH, high density cholesterol HDL, low density cholesterol LDL and triglycerides TAG) in a group of women with PCOS and a healthy control group. Levels of evaluated blood lipids in women with PCOS and the healthy control group were within the normal range.

What is the benefit of screening for thyroid function in pregnant women in the detection of newly diagnosed thyropathies?

Background: Thyroid gland disturbances are the most common endocrine disorders in pregnancy. There are some particular recommendations for the investigation of women in risk groups, but no consensus guidelines for general screening exists at present in the Czech Republic.

Aim: The aim of our study was to determine whether universally conducted screening of pregnant women would reveal a significant number thyropathies.

Steroid profiling in pregnancy: a focus on the human fetus.

In this review we focused on steroid metabolomics in human fetuses and newborns and its role in the physiology and pathophysiology of human pregnancy and subsequent stages of human life, and on the physiological relevance of steroids influencing the nervous systems with regards to their concentrations in the fetus. Steroid profiling provides valuable data for the diagnostics of diseases related to altered steroidogenesis in the fetal and maternal compartments and placenta. We outlined a potential use of steroid metabolomics for the prediction of reproductive disorders, misbalance of hypothalamic-pituitary-adrenal axis, and impaired insulin sensitivity in subsequent stages of human life.

[Basic anthropometric characteristics and their relationship with the metabolism of saccharides in women with PCOS].

Aim Of Study: To determine basic anthropometric characteristics and their relationship with the metabolism of saccharides in women with PCOS in the Olomouc region.

Type Of Study: Retrospective study of the results of 72 women with PCOS examined in the endocrinology clinic.

Material And Method: The study entailed the processing of data gained on the basis of examination of women sent to endocrinology clinic for examination in the years 2008-2010, who corresponded to the diagnostic criteria for PCOS according to the Rotterdam consensus.