Publications by authors named "Saranya K"

We report a detailed experimental study of the structural, magnetic and electrical properties of La and Ru doped (Sr1-x Lax)2Ir1-xRuxO4 (x= 0.05, 0.15).

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Introduction Modern dentistry prioritizes aesthetic outcomes, making root coverage for gingival recession a key focus. Various approaches, including autologous grafts, address this issue, yet no substitute matches the properties of autogenous connective tissue grafts. The innovative collagen-chitosan-bioglass scaffold presents a promising solution, surpassing the limitations of the traditional methods.

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Cancer drug response (CDR) prediction is an important area of research that aims to personalize cancer therapy, optimizing treatment plans for maximum effectiveness while minimizing potential negative effects. Despite the advancements in Deep learning techniques, the effective integration of multi-omics data for drug response prediction remains challenging. In this paper, a regression method using Deep ResNet for CDR (DRN-CDR) prediction is proposed.

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The local disruptions caused by the genes of one disease can influence the pathways associated with the other diseases resulting in comorbidity. For gene therapies, it is necessary to prioritize the key genes that regulate common biological mechanisms to tackle the issues caused by overlapping diseases. This work proposes a clustering-based computational approach for prioritising the comorbid genes within the overlapping disease modules by analyzing Protein-Protein Interaction networks.

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In this research work, we have successfully synthesized the CeO/CoO/g-CN ternary nanocomposite for hydrothermal method for photocatalytic applications. The synthesized nanocomposites were characterized using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, Field emission scanning electron microscopy (FE-SEM), Transmission electron microscopy TEM, Photoluminescent spectra (PL), X-ray photoelectron spectroscopy (XPS), Brunauer- Emmett-Teller (BET) and Ultraviolet diffuse reflectance spectroscopy (UV-DRS) technique. As per the optical spectroscopic investigations CeO/CoO/g-CN ternary nanocomposite exhibited the high optical absorption range and its band gap is reduced from 2.

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Background Periodontal regeneration aims for the three-dimensional reconstruction of bone defects, and over the years, bone grafts with or without barrier membranes have provided us with promising results. Particulate bone grafts can be classified according to the source of procurement as autografts, allografts, xenografts, and alloplasts. Bioglass, an innovative alloplast that uses silica particles as a matrix incorporated with calcium and phosphorus, has been extensively used as a propitious material for bone regeneration owing to its inherent osteogenic ability and biocompatibility but presents with various disadvantages such as slow degradation rate, low mechanical strength, and fracture resistance.

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Article Synopsis
  • Guided bone regeneration (GBR) is a technique to enhance dental implant placements in areas with insufficient bone, and researchers are seeking the optimal GBR membrane to improve healing outcomes.* -
  • A new GBR membrane was created using a mix of selenium-doped bio-glass, collagen, and gelatin, and it showed favorable surface characteristics, chemical composition, and strong antibacterial effects.* -
  • The membrane demonstrated excellent biocompatibility with zebrafish, maintaining high cell viability over time, and further studies are suggested to evaluate its effectiveness in broader applications.*
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Triple-negative breast cancer (TNBC) doesn't have well-defined molecular targets making it unable to treat with chemotherapy also have faster metastatic rate and worse survival rate. In the current study we aim to target TNBC through eco-friendly green synthesized silver nanoparticles having anti-cancer phytoconstituents from the traditional anti-cancer medicinal plant Eclipta alba. Green synthesized silver nanoparticles (AgNPs) are agglomerates of spherical shaped 40-60 nm sized showing characteristic light absorption at 437 nm, banding pattern at 1479, 1285, 1036, and 471 showing and further X-ray diffraction pattern confirm face-centered cubic crystal silver structure exist in the green synthesized silver nanoparticle preparation.

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Fluorosis, a chronic condition brought on by excessive fluoride ingestion which, has drawn much scientific attention and public health concern. It is a complex and multifaceted issue that affects millions of people worldwide. Despite decades of scientific research elucidating the causes, mechanisms, and prevention strategies for fluorosis, there remains a significant gap between scientific understanding and public health implementation.

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Semiconductor photocatalysts are promising cost-effective materials for degrading hazardous organic contaminants in water. AgPO is an efficient visible-light photocatalyst for the oxidation of water and dye degradation. The excited AgPO photocatalyst uses a hole to oxidise water or organic contaminants except the electron, which reduces Ag to Ag.

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Stress is a universal emotion that every human experiences daily. Psychologists say stress may lead to heart attack, depression, hypertension, strokes, or even sudden death. Many technical explorations like stress detection through facial expression, speech, text, physical behaviors, etc.

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Soil salinity is one of the major limiting factors of the crop production, it has been constantly increasing in agricultural land due to the impact of climate change and urbanisation. High salinity in the agrolands can lead ionic, oxidative, osmotic and water stress to crops. A potential phosphate solubilising bacterium, Curtobacterium luteum was isolated from marine environment (seagrass meadow) and was evaluated for the enhancement of plant growth promotion of three different agro plants (rice, tomato and chilli) using agro saline soil.

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The effects of Indole-3-butyric acid (IBA) supplementation in combination with nitrogen limitation on the biomass, biochemical and fatty acid composition of three selenastracean microalgae were studied. In the algae tested, nitrogen deficiency alone resulted in lower biomass output, whereas supplementation with 0.075 mM IBA resulted in increased biomass production on Selenastrum capricornutum (679 mg L), Ankistrodesmus falcatus (521 mg L) and Kirchneriella obesa (361 mg L) than their respective controls.

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Background: Water is vital for life as the body uses water in all its cells and tissues to maintain vital functions. Hence, water used for drinking should be free from all types of impurities. Acharya Sushruta has mentioned various water purification methods by keeping it in different types of vessels (silver, copper, and clay) and by adding herbs such as (seeds Linn.

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Juvenile crime or delinquency has been increasing at an alarming rate in recent times. In many countries, including India, the minimum age for criminal responsibility is 16 years. The present study aimed to estimate the probability of a south Indian adolescent either being or being older than the legally relevant age of 16 years using Demirjian's tooth formation stages.

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The effects of copper (Cu) toxicity on the growth, pigments, protein, carbohydrate, lipid and antioxidant enzyme activities of two endemic microalgae, Chaetoceros calcitrans and Nitzchia closterium from Cochin estuary were studied and compared. The 96 h median inhibition concentration (IC) of Cu for C. calcitrans was 143.

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Aim: To bridge the gap between urban and rural population, a vast number of researches are being carried out. Teledentistry is one of the technological advances in dentistry. It is defined by Cook in 1997 as "the practice of using video-conferencing technologies to diagnose and provide advice about treatment over a distance.

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We report high-precision magnetization ([Formula: see text]), magnetic susceptibility ([Formula: see text]), specific heat (C (T, H)) and 'zero-field' electrical resistivity, [Formula: see text], data taken on GdTe single crystal over wide ranges of temperature and magnetic field (H), with either [Formula: see text]-axis or [Formula: see text]-plane. [Formula: see text] and [Formula: see text] unambiguously establish that the b-axis is the easy direction of magnetization whereas any direction in the ac-plane is a hard direction. The [Formula: see text]-type anomaly in 'zero-field' specific heat, C (T, H  =  0), and an abrupt drop in [Formula: see text] (characteristic of the paramagnetic (PM) - antiferromagnetic (AFM) phase transition) are observed at the Néel temperature, [Formula: see text] K.

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Non-small cell lung cancer is a fatal disease associated with high morbidity. It is important to evaluate the effects of treatment on patient's quality of life. Quality of life can be assessed by using EORTC QLQ - C30 and EORTC QLQ - LC 13.

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The present study reports a green and sustainable method for the synthesis of titanium dioxide (TiO₂) nanoparticles (NPs) from titanium oxysulfate solution using Kondagogu gum (), a carbohydrate polymer, as the NPs formation agent. The synthesized TiO₂ NPs were categorized by techniques such as X-Ray Diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy analysis, Raman spectroscopy, scanning electron microscope- Energy-dispersive X-ray spectroscopy (SEM-EDX), Transmission electron microscopy (TEM), High-resolution transmission electron microscopy (HR-TEM), UV-visible spectroscopy, Brunauer-Emmett-Teller (BET) surface area and particle size analysis. Additionally, the photocatalytic actions of TiO₂ NPs were assessed with regard to their ability to degrade an organic dye (methylene blue) from aqueous solution in the presence of solar light.

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This paper examines the potential detoxification efficiency of heavy metals by phosphate solubilising bacteria (PSB) that were isolated from coral, sea grass and mangrove environment. Initially, four potential bacterial isolates were selected based on their phosphate solubilisation index from 42 strains and were used for the metal tolerance test. Among the four isolates, KSCAS2 exhibited maximum tolerance to heavy metals and the phenotype indicated the production of extra polymeric substances.

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The theory of glucose-responsive composite membranes for the planar diffusion and reaction process is extended to a microsphere membrane. The theoretical model of glucose oxidation and hydrogen peroxide production in the chitosan-aliginate microsphere has been discussed in this manuscript for the first time. We have successfully reported an analytical derived methodology utilizing homotopy perturbation to perform the numerical simulation.

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Thirty-one mercury-resistant bacterial strains were isolated from the effluent discharge sites of the SIPCOT industrial area. Among them, only one strain (CASKS5) was selected for further investigation due to its high minimum inhibitory concentration of mercury and low antibiotic susceptibility. In accordance with 16S ribosomal RNA gene sequences, the strain CASKS5 was identified as .

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Spatially explicit approach is essential to prioritise the ecosystems for biodiversity conservation. In the present study, the conservation status of 20 protected areas of the Western Ghats of Kerala, India, was analysed based on long-term changes in forests (1975-1985-1995-2005-2013), landscape level changes in fragmentation and forest fires (2005-2015). This study has shown that a significant forest loss occurred in protected areas before declaration.

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One-dimensional graphitized carbon nanofibers (G-CNFs) were prepared by employing facile electrospinning technique using 10 wt% of polyacrylonitrile (PAN) solution in N,N-dimethyl formamide (DMF) as precursor followed by successive stabilization, carbonization and purification processes. Cobalt sulfide (CoS) nanoparticles were grown onto G-CNFs by hydrothermal method using cobalt chloride and L-cysteine as precursors. The results of X-ray diffraction (XRD) and Raman spectroscopy confirmed the phase formation and degree of graphitization, respectively.

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