Publications by authors named "Sarala N Malladi"
Amblyopia is a developmental disorder associated with reduced performance in visually guided tasks, including binocular navigation within natural environments. To help understand the underlying neurological disorder, we used fMRI to test the impact of amblyopia on the functional organization of scene-selective cortical areas, including the posterior intraparietal gyrus scene-selective (PIGS) area, a recently discovered region that responds selectively to ego-motion within naturalistic environments (Kennedy et al., 2024).
View Article and Find Full Text PDFCurrent models of scene processing in the human brain include three scene-selective areas: the parahippocampal place area (or the temporal place areas), the restrosplenial cortex (or the medial place area), and the transverse occipital sulcus (or the occipital place area). Here, we challenged this model by showing that at least one other scene-selective site can also be detected within the human posterior intraparietal gyrus. Despite the smaller size of this site compared to the other scene-selective areas, the posterior intraparietal gyrus scene-selective (PIGS) site was detected consistently in a large pool of subjects (n 59; 33 females).
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- Researchers used high-resolution fMRI to explore how anisometropia and strabismus affect ocular dominance responses in amblyopic individuals compared to those with normal vision.
- The fMRI results showed that amblyopic participants' ocular dominance responses created larger, fused patches across visual areas, particularly in V1, while controls exhibited a more structured striped pattern.
- Notable differences emerged between the two conditions; anisometropic individuals displayed a more significant increase in V1 responses and greater amplitudes in their binocular stimuli responses compared to strabismic individuals, suggesting distinct impacts on visual processing from each condition.
Current models of scene processing in the human brain include three scene-selective areas: the Parahippocampal Place Area (or the temporal place areas; PPA/TPA), the restrosplenial cortex (or the medial place area; RSC/MPA) and the transverse occipital sulcus (or the occipital place area; TOS/OPA). Here, we challenged this model by showing that at least one other scene-selective site can also be detected within the human posterior intraparietal gyrus. Despite the smaller size of this site compared to the other scene-selective areas, the posterior intraparietal gyrus scene-selective (PIGS) site was detected consistently in a large pool of subjects (=59; 33 females).
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