Publications by authors named "Sarah Savaridas"
Breast ultrasound elastography phantoms are valued for their ability to mimic human tissue, enabling calibration for quality assurance and testing of imaging systems. Phantoms may facilitate the development and evaluation of ultrasound techniques by accurately simulating the properties of breasts. However, selecting appropriate tissue-mimicking materials for realistic and accurate ultrasound exams is crucial to ensure the ultrasound system responds similarly to real breast tissue.
View Article and Find Full Text PDFObjectives: Image monitoring is essential to monitor response to neoadjuvant chemotherapy (NACT). Whilst breast MRI is the gold-standard technique, evidence suggests contrast-enhanced spectral mammography (CESM) is comparable. We investigate whether the addition of digital breast tomosynthesis (DBT) to CESM increases the accuracy of response prediction.
View Article and Find Full Text PDFArticle Synopsis
- This study focuses on using radiomic analysis of contrast-enhanced mammographic images to distinguish between benign and malignant lesions through classification models based on a diverse data set.
- It utilized CEM images from different equipment, extracting textural features with software and comparing segmentation techniques (freehand vs. ellipsoid).
- The findings showed high diagnostic accuracy (>0.9), with ellipsoid segmentation being more effective, and suggested that using both mammographic views might not be necessary for improved accuracy.
Objective: Contrast-enhanced digital breast tomosynthesis (CE-DBT) is a novel imaging technique, combining contrast-enhanced spectral mammography and tomosynthesis. This may offer an alternative imaging technique to breast MRI for monitoring of response to neoadjuvant chemotherapy. This paper addresses patient experience and preference regarding the two techniques.
View Article and Find Full Text PDFObjectives: To identify associations between baseline ultrasound (US) and mammographic features and metastasis free survival (MFS) in women receiving neo-adjuvant chemotherapy (NACT) for breast cancer.
Methods: The data were collected as part of an ethically approved prospective study. Women with invasive breast cancer receiving NACT who were metastasis free at diagnosis were included.
Article Synopsis
- The study investigates the relationship between baseline mammographic and ultrasound features and the likelihood of achieving complete pathological response (pCR) in breast cancer patients undergoing neoadjuvant chemotherapy (NACT).
- It analyzes the imaging characteristics and how they correlate with pCR, finding significant associations with features like core biopsy grade, absence of posterior shadowing on ultrasound, and lack of mammographic spiculation.
- Results indicate that pCR is linked to these features, especially in HER-2 positive tumors, potentially guiding treatment decisions and patient discussions.
Introduction: The importance of internal mammary nodes (IMNs) in the staging and treatment of breast cancer patients is controversial.
Methods: A retrospective cohort of patients diagnosed with primary breast cancer over a 4-year period (January 2009 to December 2012) was assessed. The number and size of any IMNs visible on spiral computed tomography (CT) were recorded.
Background: A retrospective, cross-sectional study was performed to compare the rates of skeletal maturation in Scottish populations 25 years apart (1980-2005).
Methods: Two cohorts of sequentially radiographs were identified from patients at a Scottish pediatric hospital in 1980 and 2005. All radiographs were performed after trauma.