Publications by authors named "Sarah Sadat"

Article Synopsis
  • - Traumatic spinal cord injury (SCI) leads to severe physical and autonomic issues, and current treatments are often ineffective, highlighting a need for better therapies.
  • - The initial injury triggers secondary molecular processes in various cell types that exacerbate spinal cord damage, presenting potential targets for new treatments.
  • - This article reviews key intracellular signaling pathways—like MAPK, PI3K-AKT-mTOR, and others—that could be crucial for developing effective therapies post-SCI, using recent advancements in research for insights.
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A spinal cord injury (SCI) can be a devastating condition in children, with profound implications for their overall health and quality of life. In this review, we aim to provide a concise overview of the key aspects associated with SCIs in the pediatric population. Firstly, we discuss the etiology and epidemiology of SCIs in children, highlighting the diverse range of causes.

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Cutaneous T-cell lymphoma (CTCL) is a malignancy of skin-homing T cells. A major feature of CTCL is profound immunosuppression, such that patients with advanced mycosis fungoides or Sézary syndrome have been compared with patients with advanced HIV disease and are susceptible to opportunistic infection. The etiology of this immunosuppression is unclear.

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