Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62.

Connexin (Cx) gap junction proteins are expressed by a multitude of cells and function as plasma membrane hemichannels or dock to form intercellular communication tunnels. Whilst Cx43 has garnered considerable attention, less is known about the structure and function of Cx62 channels. Platelets and megakaryocytes express Cx37, Cx40 and Cx62, which contribute to hemostatic and thrombotic responses.

Relationship between body image and stimulant use among Canadian adolescents.

This study investigated the relationship between body image, dieting, disordered eating behaviors, and stimulant use in a sample of more than 30,000 British Columbian students. For both males and females, significant associations were found between stimulant use and body satisfaction, binging and purging, and efforts to lose weight.