Am J Respir Crit Care Med
January 2024
Acute lung injury (ALI) carries a high risk of mortality but has no established pharmacologic therapy. We previously found that experimental ALI occurs through natural killer (NK) cell NKG2D receptor activation and that the cognate human ligand, MICB, was associated with ALI after transplantation. To investigate the association of a common missense variant, , with ALI.
View Article and Find Full Text PDFImportance: Low back and neck pain are often self-limited, but health care spending remains high.
Objective: To evaluate the effects of 2 interventions that emphasize noninvasive care for spine pain.
Design, Setting, And Participants: Pragmatic, cluster, randomized clinical trial conducted at 33 centers in the US that enrolled 2971 participants with neck or back pain of 3 months' duration or less (enrollment, June 2017 to March 2020; final follow-up, March 2021).