Publications by authors named "Sarah M V Brockbank"
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Synopsis of recent research by authors named "Sarah M V Brockbank"
- Sarah M V Brockbank’s research predominantly focuses on the role of matrix metalloproteinases (MMPs) and their inhibitors in cartilage degradation and inflammatory processes, with particular emphasis on osteoarthritis (OA) and cardiovascular disease.
- Significant findings include the identification of MMP-17 as crucial for aggrecan degradation in OA, and the expression profiling of various metalloproteinases and their inhibitors in normal and OA-affected cartilage.
- Additionally, Brockbank has contributed to the understanding of cell-penetrating peptides for the delivery of therapeutics, evaluating their efficacy, uptake mechanisms, and toxicity in various cell lines.
