Publications by authors named "Sarah M Harnden"

Article Synopsis
  • Leukotrienes may play a role in acute COPD exacerbations, but their modifiers like zileuton haven't been thoroughly tested for this purpose.
  • A study was conducted to assess the safety and effectiveness of zileuton versus a placebo for hospitalized COPD patients, focusing on hospital stay duration and treatment failure rates.
  • The results showed no significant difference in hospital stay or treatment failures between the two groups, though zileuton did reduce certain leukotriene levels, indicating it might be safe but not necessarily effective in improving patient outcomes in this context.
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