The Implementation of "McGill's Big 3" in an Individual with an Acquired Brain Injury who Ambulates Independently: A Case Report.

Background: Improved function, through balance and mobility, has been demonstrated in individuals with an acquired brain injury (ABI) following various exercise interventions; however, the feasibility of implementing "McGill's Big 3" exercises, typically prescribed for people with back pain, to improve function in people with ABI requires investigation.

Objective: The aim of this case report was to determine the feasibility of implementing "McGill's Big 3" exercises on balance and mobility when prescribed to an individual with an ABI who ambulates independently.

Methods And Materials: A 40-year-old female with an ABI completed an 8-week exercise intervention consisting of "McGill's Big 3" exercises.

Comparison of real-time microvascular abnormalities in pediatric and adult sickle cell anemia patients.

The conjunctival microcirculation in 14 pediatric and eight adult sickle cell anemia (SCA) patients was studied using computer-assisted intravital microscopy. The bulbar conjunctiva in SCA patients in both age groups exhibited a blanched/avascular appearance characterized by decreased vascularity. SCA patients from both age groups had many of the same abnormal morphometric [vessel diameter, vessel distribution, morphometry (shape), tortuosity, arteriole:venule (A:V) ratio, and hemosiderin deposits] and dynamic [vessel sludging/sludged flow, boxcar blood (trickled) flow, and abnormal flow velocity] abnormalities.