Purpose: To investigate the relationship between the occurrence of transient cardiac ischaemic episodes and variations in the ambulatory 24-h blood pressure and heart rate measurements in a group of unselected glaucoma patients.
Design: Prospective study.
Participants: Twenty-four consecutive glaucoma patients and 23 age-matched controls were included in the present study.
Purpose: To investigate the presence of silent cardiac ischaemic episodes and the status of autonomic function in consecutive, newly diagnosed and untreated primary open-angle glaucoma patients.
Methods: Twenty-four consecutively diagnosed glaucoma patients and 22 age-matched controls were subjected to ambulatory 24-h blood pressure (BP) and electrocardiogram (ECG) monitoring by using Cardiotens-01 (Meditech Ltd). Based on the ECG recordings, heart rate variability (HRV) frequency domain parameters [low-frequency (LF), high-frequency (HF) and LF/HF ratio] were calculated and analysed in the two study groups.
Purpose: To assess the level of plasma glutathione in patients with untreated primary open-angle glaucoma.
Methods: Twenty-one patients with newly diagnosed primary open-angle glaucoma and 34 age- and gender-matched control subjects were subjected to a blood analysis to detect the level of circulating glutathione in its reduced and oxidized forms. The effect of age, gender, and systemic blood pressure on circulating glutathione levels was also analyzed.
Purpose: To assess systemic and ocular vascular reactivity in response to warm and cold provocation in untreated patients with primary open-angle glaucoma and normal control subjects.
Methods: Twenty-four patients with primary open-angle glaucoma and 22 normal control subjects were subjected to a modified cold pressor test involving immersion of the right hand in 40 degrees C warm water followed by 4 degrees C cold water exposure, and finger and ocular blood flow were assessed by means of peripheral laser Doppler flowmetry and retinal flowmetry, respectively. Finger and body temperature as well as intraocular pressure, systemic blood pressure, systemic pulse pressure, heart rate, and ocular perfusion pressure were also monitored.
Graefes Arch Clin Exp Ophthalmol
August 2002
Background: Reports of short-wavelength pathway dysfunction in retinal eye disease suggest that short-wavelength automated perimetry may be a useful technique for the investigation of central visual function. The aim of this study was to adapt existing statistical procedures used for the investigation of 30-2 short-wavelength automated perimetry to the 10-2 program of the Humphrey Field Analyser.
Methods: A four- or six-point linear interpolation procedure was used to calculate normal visual field sensitivity for each of the 68 stimulus locations of the 10-2 program using empirical normal data from 51 normal subjects examined using the 30-2 program.
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