Publications by authors named "Sarah L Gullett"
Biochim Biophys Acta
December 2011
Article Synopsis
- Carbonic anhydrase VI (CA VI) plays a role in protecting tooth enamel from cavities by being secreted from salivary glands, and its lower levels are linked to higher cavity rates in humans.
- Research using Car6(-/-) mice, which lack CA VI, showed these mice had unexpectedly fewer caries than normal mice after exposure to the cavity-causing bacteria Streptococcus mutans.
- The study suggests CA VI may actually contribute to cavity development by influencing the oral microbiota and producing acids in dental plaque.
