Publications by authors named "Sarah Kozey-Keadle"

Purpose: The purpose of this study was to determine the criterion validity of Activities Completed over Time (ACT24), an automated previous-day recall tool designed for mobile devices for 1) estimating sedentary versus active time compared with an activPAL, and 2) estimating time spent in activity domains (e.g., work, household, leisure) compared with direct observation (DO).

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Background: Moderate-vigorous physical activity (MVPA) reduces colon cancer risk; however, it is unclear how the timing of MVPA throughout the adult life course impacts colon cancer risk. We evaluated whether maintenance and changes in MVPA levels over time are associated with colon cancer risk.

Methods: We assessed 293,198 adults ages 50 to 71 years in the NIH-AARP Diet and Health Study.

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Background: It is important for sport scientists and health professionals to have estimative methods for energy demand during different physical activities. The metabolic equivalent of task (MET) provides a feasible approach for classifying activity intensity as a multiple of the resting metabolic rate (RMR). RMR is generally assumed to be 3.

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Purpose: This study aimed to examine the shape of the relationship between physical activity (PA) and total energy expenditure (TEE) and to explore the role of energy balance status (negative, stable, positive) in influencing this association.

Methods: Cross-sectional. Participants were 584 older adults (50-74 yr) participating in the Interactive Diet and Activity Tracking in AARP study.

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To determine the feasibility, acceptability and preliminary efficacy of an eHealth intervention with charity-based incentives to increase physical activity (PA) among young adult cancer survivors. Participants were randomized into two groups: PA (N = 25; Fitbit, step goal, electronic weekly newsletter) or PA + Charity (N = 26; same as PA plus charity donation if step goal achieved). At baseline and 12 weeks, steps/day were assessed using an activPAL.

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Background: This study reexamines the energy cost of lower intensity activities compared to the 2011 Adult Compendium of Physical Activities.

Methods: Participants (n = 32, age = 35 [13.8] y, 16 females) wore a portable metabolic system (COSMED), during 5 different conditions: sitting quietly, watching TV, sitting while working, driving, and walking at 2.

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Purpose: The present study estimated the long-term reproducibility of accelerometer-based measures over 6 months in adults and the implications for statistical power, and attenuation in regression coefficients for future activity-disease studies.

Methods: We used data from 914 adults in the Interactive Diet and Activity Tracking in AARP study. Participants wore an activPAL 3 (AP) and an ActiGraph GT3X (AG) twice, 6 months apart.

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Body-worn devices that estimate physical behavior have tremendous potential to address key research gaps. However, there is no consensus on how devices and processing methods should be developed and evaluated, resulting in large differences in summary estimates and confusion for end users. We propose a phase-based framework for developing and evaluating devices that emphasizes robust validation studies in naturalistic conditions.

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Purpose: Sedentary behavior is associated with poor health outcomes including obesity, lower quality of life, and mortality in breast cancer survivors. This study sought to identify motivational, demographic, and disease characteristics of breast cancer survivors who engage in greater amounts of sedentary behavior.

Methods: Multivariate linear regression models estimated associations between demographic, disease, and health characteristics with reported sitting in breast cancer survivors (n = 279; M = 60.

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Purpose: Interest in a variety of physical behaviors (e.g., exercise, sitting time, sleep) in relation to health outcomes creates a need for new statistical approaches to analyze the joint effects of these distinct but inter-related physical behaviors.

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Studies for the associations between physical activity and disease risk have been supported by newly developed wearable accelerometer-based devices. These devices record raw activity/movement information in real time on a second-by-second basis and the data can be converted to a variety of summary metrics, such as energy expenditure, sedentary time and moderate-vigorous intensity physical activity. Here we review some of the methods used to analyze the accelerometer data and the R packages that can generate activity related variables from raw data.

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Introduction: The goal of this study was to describe differences in time use and energy expenditure associated with exercise, prolonged TV viewing, and work days in a longitudinal study of older adults.

Methods: Participants were 1,020 adults who completed previous-day recalls that provided a profile of the use of time in sedentary and physical activity. Time use and physical activity energy expenditure were predicted for each type of day (exercise, prolonged TV, work) using linear mixed models, adjusting for age, sex, season of the year, and day of the week.

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Purpose: To compare estimates of moderate-vigorous physical activity (MVPA) duration derived from accelerometers calibrated only to walking and running activities to estimates from calibrations based on a broader range of lifestyle and ambulatory activities.

Methods: In a study of 932 older (50-74 yr) adults we compared MVPA estimates from accelerometer counts based on three ambulatory calibration methods (Freedson 1952 counts per minute; Sasaki 2690 counts per minute; activPAL 3+ METs) to estimates based on calibrations from lifestyle and ambulatory activities combined (Matthews 760 counts per minute; Crouter 3+ METs; Sojourn3x 3+ METs). We also examined data from up to 6 previous-day recalls describing the MVPA in this population.

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We take a functional data approach to longitudinal studies with complex bivariate outcomes. This work is motivated by data from a physical activity study that measured 2 responses over time in 5-minute intervals. One response is the proportion of time active in each interval, a continuous proportions with excess zeros and ones.

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Introduction/purpose: To assess the utility of measurement methods that may be more accurate and precise than traditional questionnaire-based estimates of habitual physical activity and sedentary behavior we compared the measurement properties of a past year questionnaire (AARP) and more comprehensive measures: an internet-based 24-h recall (ACT24), and a variety of estimates from an accelerometer (ActiGraph).

Methods: Participants were 932 adults (50-74 yr) in a 12-month study that included reference measures of energy expenditure from doubly labeled water (DLW) and active and sedentary time via activPAL.

Results: Accuracy at the group level (mean differences) was generally better for both ACT24 and ActiGraph than the AARP questionnaire.

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A mixed effect model is proposed to jointly analyze multivariate longitudinal data with continuous, proportion, count, and binary responses. The association of the variables is modeled through the correlation of random effects. We use a quasi-likelihood type approximation for nonlinear variables and transform the proposed model into a multivariate linear mixed model framework for estimation and inference.

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Purpose: The purpose of this study was to explore breast cancer survivors' interest in and preferences for technology-supported exercise interventions.

Methods: Post-treatment survivors [n = 279; M  = 60.7 (SD = 9.

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Background: This paper tested whether a physical activity index (PAI) that integrates PA-related behaviors (ie, moderate-to-vigorous physical activity [MVPA] and TV viewing) and performance measures (ie, cardiorespiratory fitness and muscle strength) improves prediction of health status.

Methods: Participants were a nationally representative sample of US adults from 2011 to 2012 NHANES. Dependent variables (self-reported health status, multimorbidity, functional limitations, and metabolic syndrome) were dichotomized.

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Unlabelled: The activPAL (AP) monitor is well established for distinguishing sitting, standing, and stepping time. However, its validity in predicting time in physical activity intensity categories in a free-living environment has not been determined.

Purpose: This study aimed to determine the validity of the AP in estimating time spent in sedentary, light, and moderate-to-vigorous physical activity (MVPA) in a free-living environment.

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Introduction: Accelerometers are used increasingly in large epidemiologic studies, but, given logistic and cost constraints, most studies are restricted to a single, 7-day accelerometer monitoring period. It is unknown how well a 7-day accelerometer monitoring period estimates longer-term patterns of behavior, which is critical for interpreting, and potentially improving, disease risk estimates in etiologic studies.

Methods: A subset of participants from the Women's Health Study (N=209; mean age, 70.

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Introduction: The way physical activity (PA) and sedentary behavior (SB) are accumulated throughout the day (i.e., patterns) may be important for health, but identifying measurable and meaningful metrics of behavioral patterns is challenging.

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Motivated by physical activity data obtained from the BodyMedia FIT device (www.bodymedia.com), we take a functional data approach for longitudinal studies with continuous proportional outcomes.

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Background: Moderate-to-vigorous-intensity physical activity is recommended to maintain and improve health, but the mortality benefits of light activity and risk for sedentary time remain uncertain.

Objectives: Using accelerometer-based measures, we 1) described the mortality dose-response for sedentary time and light- and moderate-to-vigorous-intensity activity using restricted cubic splines, and 2) estimated the mortality benefits associated with replacing sedentary time with physical activity, accounting for total activity.

Design: US adults (n = 4840) from NHANES (2003-2006) wore an accelerometer for ≤7 d and were followed prospectively for mortality.

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