Publications by authors named "Sarah Koske"

Leafy green vegetables are a common source of Shiga toxin-producing Escherichia coli O157:H7 (STEC O157) foodborne illness outbreaks. Ruminant animals, primarily cattle, are the major reservoir of STEC O157. Epidemiological, traceback and field investigations were conducted to identify potential outbreak sources.

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Article Synopsis
  • In 2017, a multistate investigation confirmed Seoul virus (SEOV) infections in both humans and pet rats, with 147 humans and 897 rats tested across multiple states.
  • Seven reported symptoms, with three requiring hospitalization, but all recovered; the study identified significant correlations between human infections and rat antibody/virus presence.
  • Genomic analysis showed a high similarity of SEOV strains, highlighting transmission through the trade of pet rats, leading to recommendations for enhanced prevention measures among pet rat owners and public health officials.
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In December 2016, the Wisconsin Department of Health Services (WDHS) notified CDC of a patient hospitalized with fever, leukopenia, elevated transaminases, and proteinuria. The patient owned and operated an in-home rattery, or rat-breeding facility, with approximately 100 Norway rats, primarily bred as pets. A family member developed similar symptoms 4 weeks later, but was not hospitalized.

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During a 3-mo period, 9 of the 15 New Zealand White rabbits used in a heart failure study developed a hemolytic anemia. The heart failure model involved the creation of an aortic insufficiency (AI) followed 2 to 6 wk later by the creation of an aortic stenosis (AS). None of the 9 animals that developed hemolytic anemia responded to medical management, and 6 of the 9 were euthanized for humane concerns.

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