Valproic acid levels in neurodevelopmental disorders: correlation with CYP and SULT genes using LC-MS/MS.

Background: Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs worldwide, which is used to treat migraines, bipolar disorder, and anxiety. However, VPA is associated with a wide range of side effects. This study evaluates therapeutic drug monitoring (TDM) in individuals with neurodevelopmental disorders.