Tuning stable noble metal nanoparticles dispersions to moderate their interaction with model membranes.

Hypothesis: The properties of stable gold (Au) nanoparticle dispersions can be tuned to alter their activity towards biomembrane models.

Experiments: Au nanoparticle coating techniques together with rapid electrochemical screens of a phospholipid layer on fabricated mercury (Hg) on platinum (Pt) electrode have been used to moderate the phospholipid layer activity of Au nanoparticle dispersions. Screening results for Au nanoparticle dispersions were intercalibrated with phospholipid large unilamellar vesicle (LUV) interactions using a carboxyfluorescein (CF) leakage assay.

Reactivity of electrochemically generated rhenium (II) Tricarbonyl alpha-diimine complexes: a reinvestigation of the oxidation of luminescent Re(CO)3(alpha-Diimine)Cl and related compounds.

The oxidative electrochemistry of luminescent rhenium (I) complexes of the type Re(CO) 3(LL)Cl, 1, and Re(CO) 3(LL)Br, 2, where LL is an alpha-diimine, was re-examined in acetonitrile. These compounds undergo metal-based one-electron oxidations, the products of which undergo rapid chemical reaction. Cyclic voltammetry results imply that the electrogenerated rhenium (II) species 1 ( + ) and 2 ( + ) disproportionate, yielding [Re(CO) 3(LL)(CH 3CN)] (+), 7, and additional products.