Publications by authors named "Sarah Katzburg"
Purpose: The most frequent complications after rotator cuff repair (RCR) are non-healing and re-tear. Age and gender are both proven risk factors for faulty RCR. This study analyzed the effects of female sex steroids and calciotropic hormones on tendon-derived cell characteristics.
View Article and Find Full Text PDFArticle Synopsis
- Thromboprophylaxis is important for preventing deep vein thrombosis after surgery, but anticoagulants like rivaroxaban can lead to systemic osteoporosis, impacting fracture healing.
- Rivaroxaban specifically inhibits factor Xa, which is crucial in blood clotting, and this study assesses its direct effects on osteoblastic cells from humans.
- Results showed that rivaroxaban significantly reduced DNA synthesis and energy metabolism in these cells, but it had a minor effect on alkaline phosphatase activity and did not hinder bone mineralization, suggesting it affects initial bone formation stages without interfering with later mineralization.