Publications by authors named "Sarah J Swerdlow"

Seven bacteriophages were isolated from soil in Pennsylvania and Wisconsin using the host . These bacteriophages range in the number of predicted genes encoded, from 25 to 91, and are distributed across actinobacteriophage clusters EB, EC, EE, and EK.

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BabyYoda and Lynlen are two cluster EB phages that were discovered at Thiel College using NRRL B-24224. Both BabyYoda and Lynlen are predicted to be lytic, with siphovirus morphologies, with genome sizes of 41,557 and 41,448 base pairs, respectively.

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Article Synopsis
  • - The study investigates the implementation and educational benefits of course-based research experiences (CRE) in STEM education over three years, involving 102 instructors from the SEA-PHAGES program.
  • - The research includes surveys and feedback sessions to understand instructors' perspectives on the goals and teaching practices of CRE, ultimately utilizing qualitative content analysis.
  • - Findings reveal three instructional models for CRE teaching: 1) acting as a scientist and generating data, 2) teaching procedural knowledge, and 3) promoting project ownership, which help inform new instructors and institutions about effective CRE instruction.
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Course-based undergraduate research experiences (CUREs) provide a way for students to gain research experience in a classroom setting. Few examples of cell culture CUREs or online CUREs exist in the literature. The Cell Biology Education Consortium (CBEC) provides a network and resources for instructors working to incorporate cell-culture based research into the classroom.

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The lacI gene of Escherichia coli has been a highly useful target for studies of mutagenesis, particularly for analysis of the specificity (spectrum) of mutations generated under a variety of conditions and in various genetic backgrounds. The gene encodes the repressor of the lac operon, and lacI-defective mutants displaying constitutive expression of the operon are readily selected. DNA sequencing of the lacI mutants has often been confined to the N-terminal region of the protein, as it presents a conveniently short target with a high density of detectably mutable sites.

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