Synopsis of recent research by authors named "Sarah J Fyson"
- Sarah J Fyson's research primarily focuses on the role of GABAergic signaling and noradrenergic systems in modulating nociception and seizure activity in rodent models.
- Key findings include the demonstration that optoactivation of locus ceruleus neurons can lead to both increases and decreases in thermal nociception, suggesting a complex role in pain modulation.
- Additionally, Fyson's work reveals mechanisms of enhanced tonic GABAA inhibition in absence epilepsy, highlighting the importance of GABA transporter GAT-1 in controlling seizure activity and its implications for understanding epilepsy pathology.
